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Date Published: 11/07/2022
Online Published: 11/07/2022
Abstract Views: 71
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DOI: https://doi.org/10.55046/vjrnm.14.318.2013
Issue
No. 14 (2013)
Section
Scientific research
How to Cite
Nguyen , D. T., Pham, M. T., & Le, V. T. (2022). The impact of early recanalization on the growth and the prognosis of brain acute ischemic stroke. Vietnamese Journal of Radiology and Nuclear Medicine, 14, 220-225. https://doi.org/10.55046/vjrnm.14.318.2013

The impact of early recanalization on the growth and the prognosis of brain acute ischemic stroke

Dr Nguyen Duy Trinh1, professor Pham Minh Thong2, Dr Le Van Thinh3
1 NCS Course 29, University Hanoi Medical School
2 Professor, PhD University of Medicine Hanoi, Department of Diagnostic Imaging Bach Mai Hospital's photo.
3 Prof., PhD, Department of Neurology - Bach Mai Hospital.

Main Article Content

Abstract

Purpose: to study the impact of early recanalization on the growth and the outcomes of the brain acute ischemia. Method:
Cerebral MRI was performed in 53 stroke ischemia patients (from 1/2010 to 6/2013) with our stroke protocols (T2*, FLAIR, Diffusion, perfusion and MR angiography) before 6h from onset, using 1.5tesla Siemens system. We ruled out the patients who had no arterial occlusion on TOF sequence. These patients were treated at Bach mai Hospital with IV thrombolysis, IA thrombectomy (solitaire stent) or without specific treatment. A second MRI was performed at 24h after onset. The patients were divided in to 2 groups: recanalization and non-recanalization. We compared the mean infarcted volume before and after treatment of the 2 groups and between the initial and the second MRI of the each group. We compared also the rate
of hemorrhage transformation and the clinical outcomes (modified Rankin Scale) at 3 months of the two groups to assess the impact of early racanalization on ischemic stroke
Results: 53 patients (31 recanilized, 22 non- racanilized). No difference about the age, time from onset, NIHSS, initial volume
infracted between 2 groups. The final volume of infaction was 54cm3 versus 141cm3 for the recanalized and non- recanalized
patients (p=0.029). An increased volume of the infarction for nonrecanalized patient group (54 versus 141cm3) with significant
difference (p=0.0009). There was no difference of symptomatic hemorrhage rate (9% versus 9.6%, p=0.99) between the nonrecanalized and recanalized group. Good clinical outcomes (mRs ≤ 2) was 64.5% versus 22% for the recanalized and non- recanalazed group, p=0.13. Among the patient without recanalization, there were 4 patients died (18%) and 3 patients with mRs 5 at 3 months.
Conclusion: Early recanalazation reduces the growth of ischemic lesion and it is strongly associated with improved functional
outcomes.

Article Details

References

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