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Role of diffusion weighted mr imaging in the differentiation between brain abscess and cystic/necrotic brain tumors
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Abstract
SUMMARY
Objective: To evaluate the role of diffusion-weighted MR Imaging in the differentiation between brain abscess and cystic/necrotic brain tumors.
Material and method: A cross-sectional study was conducted on 53 individuals presenting with rim enhancement intra-axial mass on brain MR image at Da Nang Hospital from August 2012 to August 2013. Diffusion weighted image were also acquired with b value were 0, 50, 1000 using 1.5T Phillp Achieva MR system.
Results: 28 patients had brain abscesses and 23 were diagnosed with brain tumors pathologically. The sensitivity and specificity of MRI in the diagnosis of brain abscess were 96.4% and 96%, respectively. PPV was 96.4% and NPV was 96%. There was a statistically
significant difference in mean central ADC value between abscess and tumor, as 0.71 ± 0.24 x 10-3 mm2/s and 2.23 ± 0.44 x 10-3 mm2/s (p = 0,004) respectively. Mean peripheral ADC value showed no difference between 2 groups, as 0.78±0.26 x 10-3 mm2/s for abscess and 0.82±0.28 x 10-3 mm2/s for tumor (p = 0,132). At cut-off point of ADC ≤ 0.86 x 10-3 mm2/s, ROC curve for ADC showed 94.6% sensitivity and 100% specificity.
Conclusion: Diffusion-weighted MR image had high sensitivity and specificity in differentiation between brain abscess and cystic/necrotic tumor.
Article Details
Keywords
Diffusion-weighted MR image, brain abscess, brain tumor, ADC value
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