Applications ofradiation technology in the diagnosis and treatment of cancer

Dr Mai Trong Khoa1
1 Deputy Director of Bach Mai Hospital Director of the Center for Nuclear Medicine and Cancer tumor, Bach Mai Hospital

Main Article Content

Abstract

Incidence and mortality rates of cancer are currently on the top of disease pattern and the number is increasing and increasing worldwide. The impact of screening program for early diagnosis has been proved their important roles in the war against cancer because it helps increase the cure rates, decrease the mortality and morbidity rates, and therefore, reduce the economic-social burden. Advances in diagnostic imaging techniques, especially the hybrid imaging (Xray and Nuclear Medicine) such as PET/CT, SPECT/CT, PET/MRI, is important in accurate staging and these help choose the optimized treatment options to prolong survival while improve the quality of life. The treatment outcomes of cancer has certain remarkable advances based on variety of researches to modify, promote and strengthen the traditional treatments (surgery-chemotherapy-radiation) such as laparoscopic surgery, combined chemo-regimens, intensity modulated radiation therapy, volumetric modulated arc therapy, stereotactic radiation therapy, radiosurgery, PET/CT simulation, radioactive seeds implant, selective internal radiation therapy,
intraoperative radiation therapy, ... as well as the emerge of new methods such as targeted therapy, immunotherapy,
radioimmunotherapy, proton therapy and heavy ion. Treatment of cancer is now becoming the “invidualized treatment”
with advances in biochemistry and histophathology that helps identify characteristics of tumors individually . To achieve the most optimal outcomes, cancer should be approached by a mulitprofessional team including biochemistry, immunology, histopathology, surgical oncology, medical oncology and radiation oncology.

Article Details

References

1. Mai Trọng Khoa, Nguyễn Xuân Cử. Một số tiến bộ về kỹ thuật xạ trị ung thư và ứng dụng lâm sàng. Nhà Xuất bản Y học (2012).
2. Mai Trọng Khoa. Atlas PET/CT một số bệnh ung thư ở người Việt Nam. Nhà Xuất bản Y học (2012).
3. Cai J., Ma H., Huang F., et al. Correlation of bevacizumab-induced hypertension and outcomes of metastatic colorectal cancer patients treated with bevacizumab: a systematic review and meta-analysis. World Journal of Surgical Oncology 2013; 11:306.
4. Flaherty K.T., Infante J.R., Daud A. et al. Combined BRAF and MEK inhibition in melanoma with BRAF V600 mutations. New England Journal of
Medicine 2012; 367(18):1694-1703.
5. Gore L., DeGregori J., Porter C.C. Targeting developmental pathways in children with cancer: what price success? Lancet Oncology 2013; 4(2):e70-78.
6. Petrelli F., Borgonovo K., Cabiddu M., Lonati V., Barni S. Relationship between skin rash and outcome in non-small-cell lung cancer patients treated with anti- EGFR tyrosine kinase inhibitors: A literature-based meta-analysis of 24 trials. Lung Cancer 2012; 78(1):8- 15.
7. Umberto Veronesi, Vaia Stafyla. Grand Challenges in Surgical Oncology; Front Oncol. 2012; 2: 127.