Thanh bên bài viết
Số lượt xem PDF: 75
Role of multidetector computed tomography in assessment of laryngeal cancer at hue central hospital: sharing experiences from a single center from 31 cases
Nội dung chính của bài viết
Tóm tắt
Background: The role of multidetector computed tomography (MDCT) in diagnosing and staging 31 patients with laryngeal carcinoma.
Methods: Patients with laryngeal carcinoma were diagnosed at Hue central hospital from February 2019 to July 2020. Patients were clinically diagnosed patients of laryngeal masses, were first evaluated under indirect laryngoscopy, and then sent for Computed Tomography (CT). Postimaging biopsy was undertaken via direct laryngoscopy. Imaging features of the tumor such as site, level of invasion and staging of tumor were analyzed.
Results: The mean age was 61±11 with 90% of patients are male. The risk of laryngeal cancer for those patients who were active smokers (93.5%), and alcohol consumers (67.7%). The most common symptom was hoarseness (93.5%). In CT image, more than half of the cancers were carcinoma of the glottis (29%) and two regions supraglottis and glottis
(22,6%), while the less common cancers were the subglottic (3.2%) and all three regions (9.7%) carcinoma, especially true vocal cord (67,7%) is the most common site starting carcinoma. The percentage of tumors spreading to paraglottic space and pre-epiglottic space was 50% and 30.6% respectively. The most common stage of laryngeal cancer in CT was T3 stage (35,5%). There is a weak agreement (Kappa=0.518) in staging in laryngeal cancer in CT compared to laryngoscopy.
Conclusion: MDCT is better in staging laryngeal cancer in T3, T4 stages as compared to laryngoscopy.
Chi tiết bài viết
Từ khóa
Laryngeal carcinoma, MDCT, CT, endoscopy
Tài liệu tham khảo
2. Siegel R.L., Miller K.D.,and Jemal A.(2018), “Cancer statistics, 2018”,CA Cancer J Clin, 68(1),pp. 7–30.
3. Asia S. and Asia S. (2019), Source: Globocan 2018, 2018–2019.
4. Joshi V., Wadhwa V., and Mukherji S. (2012). Imaging in laryngeal cancers. Indian J Radiol Imaging, 22(3), 209–226.
5. Pietragalla M., Nardi C., Bonasera L., et al. (2020). Current role of computed tomography imaging in the evaluation of cartilage invasion by laryngeal carcinoma. Radiol Medica, 18(1), 45-68
6. Noppadol L. et al. (2017). Clinicopathologic Findings and Treatment Outcome of Laryngectomized Patients with Laryngeal Cancer and Hypopharyngeal Cancer: An Experience in Thailand. Asian Pacific Journal of Cancer Prevention, 18(8), 2035-204.
7. Hazem M. et al. (2014). Study of the epidemiology and management of laryngeal cancer in Kasr Al - Aini Hospital. The Egyptian Journal of Otolaryngology, 30, 208-214.
8. Tanadech Dechaphunkul et al. (2011). Epidemiology, Rick factors and Overall Survival Rate of Laryngeal Cancer in Songklanagarind Hospital. J Med Assoc Thai, 94(3), 60-355
9. Markou K., Christoforidou A., Karasmanis I., et al. (2013). Laryngeal cancer: Epidemiological data from Northern Greece and review of the literature. Hippokratia, 17(4), 313–318.
10. Wang J. et al. (2016). The prognostic value of systemic and local inflammation in patients with Laryngeal squamous cell carcinoma. Onco Targets and Therapy, (9), 7177-7185.
11. Sarkar A., Sharma N., and Raghavan A. (2016). Role of computed tomography, magnetic resonance imaging, and endoscopy in pretherapeutic evaluation of laryngeal tumors. Astrocyte, 2(4), 172-178.
12. Kashyap S.K. (2017). Correlation of Endoscopic and CT scan Findings in Laryngeal Carcinoma. J Med Sci Clin Res, 5(05), 21216–21220.
13. Louay El-Sharkawya, Adel El-Antablya, Fadi Ghariba A.H. and Algarfa T. (2019). Correlation between preoperative endoscopic findings and computed tomography with postoperative histopathology in the staging of laryngeal carcinoma. Egypt J Otolaryngol, 35(1), 41–46.