Assessment left ventricular function and regional wall motion by 256-slice dualsource coronary CT angiography: a comparison with 2D transthoracic echocardiography

Tóm tắt

Objective: To compare the left ventricular (LV) function (dimensions, ejection fraction (EF), end-diastolic volume (EDV), endsystolic volume (ESV)), and regional wall motion analyzed by 256-slice Dual-source coronary angiography CT (DSCT) with 2D transthoracic echocardiography (TTE).
Materials and Methods: One-hundred twelve patients suspected of coronary artery disease underwent DSCT and 2D-TTE within 1 week for LV dimensions, EF, EDV, and ESV. Correlation between DSCT and 2D-TTE measurements was analyzed through linear regression and Bland-Altman analysis. Regional wall motion visually scored as 3 points scale (1,normal, 2, hypokinesia, 3, dysphagia, or akinesia).
Results: Average LVEF was 66,24± 13,52% (range 23-85%) on DSCT, compared with 65,72±11,31% (range 25-84%) on 2D transthoracic echocardiography. Evaluation of LVEF showed a good correlation between DSCT and 2D-TTE (r=0,715; p<0.001). Good correlations between DSCT and 2D-TTE were demonstrated for the assessment of LVEDV (r=0,732; P < 0.001) and LVESV (r= 0,841; P < 0.001). Mean differences (±SD) of 1,78 ± 24,10 mL (p <0 .05) and 0,766 ± 13,7 mL (p < 0.05) were observed between DSCT and 2D-echocardiography for LVEDV and LVESV, respectively. LVEF was slightly overestimated with DSCT (0.52 ± 9,59%;
p < 0.05). Even the LVEF calculated by DSCT and echocardiography were similer but EDV and ESV from DSCT were statistically higher than those from 2D-TTE (p < 0.05). Agreement between DSCT and 2D-TTE in regional wall motion is 96,4%, k=0,840.
Conclusion: 256-slice DSCT can provide comparable results to those using 2D-TTE for LV function measurement include EF, EDV, ESV, and regional wall motion assessment in a heterogeneous population.