Article Sidebar
Views PDF: 21
Assessment left ventricular function and regional wall motion by 256-slice dualsource coronary CT angiography: a comparison with 2D transthoracic echocardiography
Main Article Content
Abstract
Objective: To compare the left ventricular (LV) function (dimensions, ejection fraction (EF), end-diastolic volume (EDV), endsystolic volume (ESV)), and regional wall motion analyzed by 256-slice Dual-source coronary angiography CT (DSCT) with 2D transthoracic echocardiography (TTE).
Materials and Methods: One-hundred twelve patients suspected of coronary artery disease underwent DSCT and 2D-TTE within 1 week for LV dimensions, EF, EDV, and ESV. Correlation between DSCT and 2D-TTE measurements was analyzed through linear regression and Bland-Altman analysis. Regional wall motion visually scored as 3 points scale (1,normal, 2, hypokinesia, 3, dysphagia, or akinesia).
Results: Average LVEF was 66,24± 13,52% (range 23-85%) on DSCT, compared with 65,72±11,31% (range 25-84%) on 2D transthoracic echocardiography. Evaluation of LVEF showed a good correlation between DSCT and 2D-TTE (r=0,715; p<0.001). Good correlations between DSCT and 2D-TTE were demonstrated for the assessment of LVEDV (r=0,732; P < 0.001) and LVESV (r= 0,841; P < 0.001). Mean differences (±SD) of 1,78 ± 24,10 mL (p <0 .05) and 0,766 ± 13,7 mL (p < 0.05) were observed between DSCT and 2D-echocardiography for LVEDV and LVESV, respectively. LVEF was slightly overestimated with DSCT (0.52 ± 9,59%;
p < 0.05). Even the LVEF calculated by DSCT and echocardiography were similer but EDV and ESV from DSCT were statistically higher than those from 2D-TTE (p < 0.05). Agreement between DSCT and 2D-TTE in regional wall motion is 96,4%, k=0,840.
Conclusion: 256-slice DSCT can provide comparable results to those using 2D-TTE for LV function measurement include EF, EDV, ESV, and regional wall motion assessment in a heterogeneous population.
Article Details
Keywords
DSCT; Coronary Artery Disease; Left ventricular function; Echocardiography; Radiation
References
2. De Graaf FR, Schuijf JD, van Velzen JE, et al. Assessment of global left ventricular function and volumes with 320-row multidetector computed tomography: A comparison with 2D-echocardiography. J Nucl Cardiol. 2010;17(2):225-231. doi:10.1007/s12350-009-9173-y
3. Stolzmann P, Scheffel H, Trindade PT, et al. Left Ventricular and Left Atrial Dimensions and Volumes: Comparison Between Dual-Source CT and Echocardiography. Investigative Radiology. 2008;43(5):284-289. doi:10.1097/RLI.0b013e3181626853
4. Asferg C, Usinger L, Kristensen TS, Abdulla J. Accuracy of multi-slice computed tomography for measurement of left ventricular ejection fraction compared with cardiac magnetic resonance imaging and two-dimensional transthoracic echocardiography. European Journal of Radiology. 2012;81(5):e757-e762. doi:10.1016/j.ejrad.2012.02.002
5. Ko S-M, Kim Y-J, Park J-H, Choi N-M. Assessment of left ventricular ejection fraction and regional wall motion with 64-slice multidetector CT: a comparison with two-dimensional transthoracic echocardiography. BJR. 2010;83(985):28-34. doi:10.1259/bjr/38829806.
6. Bak SH, Ko SM, Jeon HJ, Yang HS, Hwang HK, Song MG. Assessment of global left ventricular function with dual-source computed tomography in patients with valvular heart disease. Acta Radiol. 2012;53(3):270-277. doi:10.1258/ar.2011.110247.
7. Kim TH, Hur J, Kim SJ, et al. Two-Phase Reconstruction for the Assessment of Left Ventricular Volume and Function Using Retrospective ECG-Gated MDCT: Comparison with Echocardiography. American Journal of Roentgenology. 2005;185(2):319-325. doi:10.2214/ajr.185.2.01850319
8. Ryo Nakazato, MD, Ph.D., Balaji K. Tamarappoo, MD, Ph.D., Assessment of left ventricular regional wall motion and ejection fraction with low-radiation dose helical dual-source CT: Comparison to two-dimensional echocardiography. Journal of Cardiovascular Computed Tomography. 2011.Vol 5, No 3, May/June 2011.