Research value of quantitative elastography of solid nodule in the diagnosis of thyroid cancer
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Abstract
SUMMARY:
Purpose: To evaluate the value of quantitative elastography of solid nodule at Tam Anh hospital, including of cut – off value, sensitivity and specificity
Materials and methods: 130 patients with 135 thyroid nodule were confirm by pathological result who underwent quantitative elastography at Tam Anh hospital from 4/2022 to 11/2023. The following parameters were used: Tissue stiffness of thyroid nodule and thyroid tissu. The diagnostic accuracy of shear wave elastography for thyroid cancer was determined by ROC analysis
Result:. The average patient age was 49 ±12 years old. The mean stiffness of malignant and benign nodules were statistically significantly different, 47,7 ± 2,7kPa vs 24,9 ± 1,3 kPa, p < 0,01. The most accurate stiffness cut-off value was 36,5 kPa for Emean, achieved a sensitivity of 82% and a specificity of 84,7% for discriminating malignant nodules from benign nodules. Another index to diffirentiate malignant and benign nodule is elasto ratio (ER). We suggest ER cut-off threshold of 1,75, the sensitivity and specificity were 84% and 78,8%,
Conclusion: Quantitative thyroid elastography was an great value noninvasive test for discriminative the malignant thyroid nodule from benign nodule.
Keyword: Solid thyroid nodule, Quantitative elastography, Elasto ratio
Keywords
Solid thyroid nodule, Quantitative elastography, Elasto ratio
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References
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