ĐÁNH GIÁ GIÁ TRỊ CHẨN ĐOÁN UNG THƯ VÚ CỦA SIÊU ÂM ĐÀN HỒI NÉN VÀ SÓNG BIẾN DẠNG

Nguyen Thi Huyen1, Nguyen Thu Huong2, Pham Minh Thong1,
1 Bach Mai Hospital
2 Vinmec Hospital

Main Article Content

Abstract

SUMMARY


Objective: Evaluating the value of B-mode ultrasound and elastography ultrasound in the diagnosis of breast cancer.
Methods: Breast lesion patients were classified BIRADS from 3 to 5 after underwent B-mode ultrasound and elastography ultrasound examination and done biopsy to have histopathological results at Bach Mai Hospital from July 2019 to February 2020.


Results: The cut-off value of fat-to-lesion ratio is 28,4 with sensitivity
(Se), specificity(Sp) and accuracy (Acc) were 76,9%; 93,3%; 85,7% respectively. The cut-off value of Elasto/B-mode ratio is 1 with Se, Sp, Acc were 100%, 73,3%; 85,7%. Se, Sp and Acc of shear-wave elastography were 100%; 97,8% and 97,5% respectively with the cut-off value is 36 kPa. Sp, Se and Acc of Tsukuba score were respectively 84,6%; 88,9%; 86,9%. B-mode ultrasound combine with shear-wave elastography has highest Se and Sp were 100%; 91,1% respectively.
Conclusion: Elastography ultrasound combine with B-mode ultrasound can upgrade or downgrade the BIRADS level, so they can increase accuracy to diagnose breast cancer especially BIRADS 3 or 4a lesions.

Article Details

References

TÀI LIỆU THAM KHẢO
1. Freddie Bray BSc, MSc, PhD, Jacques Ferlay ME. Global cancer statistics (2018) GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries.
2. Trần Văn Thuấn. “Cụm công trình nghiên cứu Dịch tễ học, ứng dụng các tiến bộ mới trong chẩn đoán, điều trị và nâng cao chất lượng sống cho người bệnh ung thư vú”
3. Ophir J., Céspedes I., Ponnekanti H. et al. (1991). Elastography: A quantitative method for imaging the elasticity of biological tissues. Ultrason Imaging, 13 (2), pages 111–134.
4. Deniz Çebi Olgun, Bora Korkmazer, Fahrettin Kılıç, (2014). Use of shear wave elastography to differentiate benign and malignant breast lesions.
5. Jung Min Chang, Woo Kyung Moon (2011). Clinical application of shear wave elastography (SWE) in the diagnosis of benign and malignant breast diseases.
6. Trần Ngân Châu V.N.T.Q. (2018). Nghiên cứu giá trị siêu âm đàn hồi ARFI trong chẩn đoán u vú lánh và ác tính. Hội Nghị Điện Quang Và Học Hạt Nhân Lần Thứ 20.
7. Itoh A., Ueno E., Tohno E. et al. (2006). Breast disease: clinical application of US elastography for diagnosis. Radiology, 239 (2), 341–350.
8. Hyo Jin Kim, Sun Mi Kim (2017). Comparison of strain and shear wave elastography for qualitative and quantitative assessment of breast masses in the same population.
9. Richard G. Barr, David Owen Cosgrove. WFUMB Guidelines and Recommendations on the Clinical Use of Ultrasound Elastography: part 2: breast. Ultrasound med boli 2015 p.1148-1160
10. Michael Golatta, Mirjam Schweitzer-Martin. Evaluation of Virtual Touch Tissue Imaging Quantification, a New Shear Wave Velocity Imaging Method, for Breast Lesion Assessment by Ultrasound.
11. Kristina Bojanic, Natasa Kaatavic. Implementation of elastography score angd stran ratio in combination with B-mode ultrasound avoids unnecessary biopsies of breast lesions. April 2017, Pages 804-816.