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The role of functional magnetic resonance imaging in evaluating the hand motor area in patients with brain tumors
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Abstract
SUMMARY
Background: Localizing the brain's functional cortex on functional magnetic resonance imaging (fMRI) plays an important role in brain tumor resection.
Objective: To investigate imaging characteristics of the hand motor
area on standardized MRI (sMRI) and fMRI in patients with brain tumors. To evaluate the correlation between lesion to motor cortex distance (LMD)
on fMRI and preoperative motor deficit.
Methods: Standardized and functional magnetic resonance images of 20 patients with rolandic brain tumors were included, all patients underwent tumor resection. Anatomic landmarks related to the hand motor area were interpreted on standardized MRI. Measure the distance between
the hand motor area localized on fMRI and the hand motor area localized
on standardized MRI. Compare the incidence of preoperative motor deficit of groups of patients with different LMDs.
Results: The rates of clearly defined anatomical landmarks related
to the hand motor area on tumor-affected hemispheres are lower than those on unaffected hemispheres. The distance between the hand motor area localized on fMRI and the hand motor area localized on standardized MRI is 17.01 ± 3.63 mm on average and there are 6 cases where this distance is greater than 20 mm. The incidence of motor deficit in the “LMD<1cm” group, the “LMD from 1 to 2 cm” group and the “LMD>2 cm” group are 75%, 50% and 0% respectively.
Conclusions: Standardized MRI should not be use to localize the
hand motor area in patients with brain tumors. LMD is correlated with
preoperative motor deficit.
Article Details
Keywords
Brain tumor, functional magnetic resonance imaging, hand motor area
References
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