Article Sidebar
Views PDF: 76
The role of functional magnetic resonance imaging in evaluating the hand motor area in patients with brain tumors
Main Article Content
Abstract
SUMMARY
Background: Localizing the brain's functional cortex on functional magnetic resonance imaging (fMRI) plays an important role in brain tumor resection.
Objective: To investigate imaging characteristics of the hand motor
area on standardized MRI (sMRI) and fMRI in patients with brain tumors. To evaluate the correlation between lesion to motor cortex distance (LMD)
on fMRI and preoperative motor deficit.
Methods: Standardized and functional magnetic resonance images of 20 patients with rolandic brain tumors were included, all patients underwent tumor resection. Anatomic landmarks related to the hand motor area were interpreted on standardized MRI. Measure the distance between
the hand motor area localized on fMRI and the hand motor area localized
on standardized MRI. Compare the incidence of preoperative motor deficit of groups of patients with different LMDs.
Results: The rates of clearly defined anatomical landmarks related
to the hand motor area on tumor-affected hemispheres are lower than those on unaffected hemispheres. The distance between the hand motor area localized on fMRI and the hand motor area localized on standardized MRI is 17.01 ± 3.63 mm on average and there are 6 cases where this distance is greater than 20 mm. The incidence of motor deficit in the “LMD<1cm” group, the “LMD from 1 to 2 cm” group and the “LMD>2 cm” group are 75%, 50% and 0% respectively.
Conclusions: Standardized MRI should not be use to localize the
hand motor area in patients with brain tumors. LMD is correlated with
preoperative motor deficit.
Article Details
Keywords
Brain tumor, functional magnetic resonance imaging, hand motor area
References
1. Lehéricy Stéphane, Duffau Hugues, Cornu Philippe, et al. (2000). Correspondence between functional magnetic resonance imaging somatotopy and individual brain anatomy of the central region: comparison with intraoperative stimulation in patients with brain tumors. Journal of neurosurgery, 92(4):589-598.
2. Wengenroth Martina, Blatow M, Guenther J, et al. (2011). Diagnostic benefits of presurgical fMRI in patients with brain tumours in the primary sensorimotor cortex. European radiology, 21(7):1517-1525.
3. Caulo Massimo, Briganti C, Mattei PA, et al. (2007). New morphologic variants of the hand motor cortex as seen with MR imaging in a large study population. American Journal of Neuroradiology, 28 (8):1480-1485.
4. Hou B. L., Bhatia S., Carpenter J. S. (2016). Quantitative comparisons on hand motor functional areas determined by resting state and task BOLD fMRI and anatomical MRI for pre-surgical planning of patients with brain tumors. Neuroimage Clin, 11:378-387.
5. Jingshan Liang, Shengyu Fang, Xing Fan, et al. (2019). Morphometry of the Hand Knob Region and Motor Function Change in Eloquent Area Glioma Patients. Clinical neuroradiology, 29 (2):243-251.
6. Bailey P. D., Zaca D., Basha M. M., et al. (2015). Presurgical fMRI and DTI for the Prediction of Perioperative Motor and Language Deficits in Primary or Metastatic Brain Lesions. J Neuroimaging, 25(5):776-84.
7. Phạm Trường Thọ (2018). Điều trị u sao bào vùng vỏ não vận động có sử dụng cộng hưởng từ chức năng trước mổ và hệ thống định vị không khung trong mổ. Luận văn bác sĩ nội trú. Đại học Y dược Thành phố Hồ Chí Minh