Core biopsies for focal hepatic lesions by ultrasound guidance
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Abstract
SUMMARY
All percutaneous US-guided biopsies for focal liver lesions performed in 37 patients. Among the 54 lesions for which the 18- gauge cutting needle was used, core biopsy was performed once in 23 lesions (62.2%), twice in 11 lesions (29.7%), and three times in 3 lesions (8.1%). The length of tissue cores was above 1cm in 44 lesions (81.5%). Three of the 54 specimens (5.6%) fragmented when placed in formalin. The common complications were 2.7%. No major complications were observed. The core biopsy specimen was sufficient for diagnosis in 36 patients (97.3%) and was insufficient in one. Histologic examination revealed various types of H.C.C (62.2%), peripherial cholangiocarcinoma (2.7%), secondary malignant tumors (8.1%), benign tumors (24.3%). There was high concordance between the histologic and cytologic results (Kappa = 0.579, p < 0.05); and very high concordance between the core biopsy and post surgery histologic results (Kappa = 0.942, p < 0.05).
Article Details
Keywords
core biopsy, focal hepatic lesions, HCC, cholangiocarcinoma
References
1. Amaral Joao Guilherme, Schwartz Jordan et al (2006), “Sonographically guided percutaneous liver biopsy in infants: a retrospective review”, AJR, 187, pp.
644-649.
2. Beckmann Max G, Bahr Matthias J et al (2009), “Clinical relevance of transjugular liver biopsy in comparison with percutaneous and laparoscopic liver biopsy”, Gastroenterology Research and Practice, pp.1-7.
3. Cevik Figen Caglan, Aykin Nevil, Naz Hasan (2010), “Complication and efficiency of liver biopsies using Trucut biopsy gun”, J Infect Dev Ctries, 4, pp. 91-95.
4. Gilmore I.T, Burroughs A et al (1995), “Indications, methods, and outcomes of percutaneous liver biopsy in England and Wales: an audit by the British Society of
Gastroenterology and the Royal College of Physicians of London”, GUT, 36, pp. 437-441.
5. Maharaj Breminand, Bhoora Ishan G (1992), “Complications associated with percutaneous needle biopsy of the liver when one, two or three specimens
are taken”, The Fellowship of Postgraduate Medicine, 68, pp. 170-173.
6. Nazarian Levon N, Feld Rick I et al (2000), “Safety and efficacy of sonographically guided random core biopsy for diffuse liver disease”, JUM, 19, pp. 537-541.
7. Simon C.H. Yu, Liew Choong T, Law Wan Y et al (2001), “US-guided percutaneous biopsy of small (<1-cm) hepatic lesions”, Radiology, 218, pp. 195-198.