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Value of average velocity of shear wave in hepatic fibrous parenchyma by using acoustic radiation force impulse imaging. (ARF I)
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Abstract
SUMMARY
Objectives: Evaluation the average velocity of shear wave in hepatic fibrosis(ARFI) according to Metavir classification.
Methods: 241 of healthy volunteers with normal liver function test values and 160 patients, diagnosed of chronic liver disease based on serologic test of hepatitis and history of alcoholic abuse, were selected for the study. Among these patients, there are 23 patients having histologic results for grading hepatic fibrosis based on Metavir classification Shear wave velocity measurements, expressed in meters per second, were taken in liver segment 7 or 8 at deepth from 3 to 4 cm below the body surface.
Results: Average velocity of shear wave in healthy liver is 1.05 ± 0.092 m/s, of fibrosis is 1.97± 0.59 m/s. A statistically significant difference in shear wave velocity between two groups is noted (P <.001).
Conclusions: Velocity of shear wave in hepatic parenchyma measured by using ARFI increase significantly in fibrous parenchyma based on histologic results.
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References
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