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CẬP NHẬT TIẾP CẬN NHANH VÀ XỬ LÝ SỚM SỐC PHẢN VỆ DO THUỐC CẢN QUANG
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Abstract
SUMMARY
Anaphylaxis to radiocontrast substance present with pruritus, urticaria, angioedema, laryngospasm, bronchospasm, hypotension, and/or loss of consciousness. Most are mild, but a small number are life-threatening. These reactions typically develop within five minutes to one hour after administration. Higher osmolality substances cause more anaphylaxis compared to lower osmolality agents or iso-osmolal agents. Most hospital now administer
nonionic lower osmolality agents routinely for its intravascular procedures.
The diagnosis of anaphylaxis is based upon the recognition of characteristic signs and symptoms. Laboratory testing is not required.
Management: The infusion of radiocontrast substance should be stopped immediately as soon as a hypersensitivity reaction is recognized. Subsequent treatment depends upon the severity of the reaction. The treatment of anaphylaxis includes adrenalin as soon as possible by intramuscular injection then intravenously if the symptoms are resistant, intravenous fluids, oxygen, diphenhydramin (antihistamin H1) and corticosteroid intravenously, intubation may be required. Particularly, patients with cardiac arrest should be managed according to advanced cardiac life support guidelines.
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References
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