Compare between DWI and fnac in dignostis thyroid cancer

Dr Le Tuan Linh1, Dr Bui Van Lenh1, Dr Nguyen Van Hieu2, Dr Nguyen Duy Hue2
1 Department of Diagnostic Imaging, Hanoi Medical University.
2 Department of Oncology, School Ha Noi medical university.

Main Article Content

Abstract

Retrospective study on 21 patients (29 thyroid nodules: 21 benign nodules, 7 malignant nodules) who were acquired the diffusion-weighted magnetic resonance imaging (DW-MRI) with 200, 300, 400, 500, 600, 700, 800 b values and ADC maps
were calculated, fine needle aspiration cytology (FNAC) were performed in 21 nodules. Diagnosis confirmed by postsurgical
histopathologic examinations. 


Results: ADC values of nodules provide useful data about the nature of a thyroid nodule, with b200 DW-MRI, the mean ADC values of thyroid nodules were 1.45±0,30x10-3mm2/s in the malignant group and 2.26±0.33x 10-3mm2/s in the benign group, with significantly different (P< 0.001). According to an ADC cut-off value of 1.98x10-3mm2/s, the sensitivity, specificity, positive predictive value, negative predictive value, and accuracy in differentiating benign from malignant thyroid nodules are calculated as 100%; 81%; 66.7%; 100% and 86.2%, respectively. The DW-MRI has the higher values than FNAC for diagnosis of thyroid cancer. We can applied DW-MRI for diagnosis of thyroid nodule in the hospital which do not have frozen section biopsies’s practice.

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