Imaging characteristics on and value MRI of myocardial viability in patients with chronic ischemic heart disease
Main Article Content
Abstract
Purposes: 1. To describe the imaging characteristics on CMR of myocardial viability in patients with chronic ischemic heart
disease; 2. To define the relationship between myocardial viability on magnetic resonance imaging (MRI) with the stenosis degree of coronary artery on invasive coronary angiography (IVA).
Materials and Methods: 37 patients with chronic ischemic heart disease were enrolled in this cross-sectional prospective
study. All patients were performed cardiac MRI and IVA during a period from 12/2011 to 8/2012 at Bach Mai Hospital. The data
analysis by using the SPSS 18.0 (Chicago, United States).
Results: 37 patients/ 27 males (73%) with mean age: 60.11 ± 11.74 year (35 - 81). Mean left ventricular systolic function (EF):
45.83 ± 12.83% (ranged 16.6 - 72%). 64.9% had EF decreased moderate to severe. 73% had reduction of ventricular contraction.
35 patients (94.6%) had late enhancement, of which 67.6% segments supplied by LAD, 64.8% had extent myocardial scar >
50%. Sensitivity and specificity of late enhancement at coronary artery stenosis ≥ 50% were 97.1%, 33.3% respectively.
Conclusion: The extent of myocardial scar had good relationship with the stenosis degree of coronary artery.
Article Details
Keywords
Cardiac MRI, Chronic ischemic disease, coronary artery.
References
2. Lê Thị Thùy Liên, (2011) Bước đầu áp dụng cộng hưởng từ tim trong chẩn đoán bệnh tim thiếu máu cục bộ mạn tính. Luận văn Bác sĩ Nội trú. Trường Đại học Y Hà Nội.
3. Nguyễn Đại Hùng Linh, (2009) Đánh giá sống còn và tưới máu cơ tim trong bệnh tim thiếu máu cục bộ. Luận văn thạc sĩ Y học. Trường Đại học Y Dược TP HCM.
4. Abdel-Aty, H, et al., (2004) Delayed
enhancement and T2-weighted cardiovascular magnetic resonance imaging differentiate acute from chronic myocardial infarction. Circulation. 109(20): p. 2411-6.
7 Cerqueira, M. D. et al, (2002) Standardized myocardial segmentation and nomenclature for tomographic imaging of the heart: a statement for healthcare professionals from the Cardiac Imaging Committee of the Council on Clinical Cardiology of the American Heart Association. Circulation. 105(4): p. 539-42.
8 Ingkanisorn, W. P. et al., (2004) Gadolinium delayed enhancement cardiovascular magnetic resonance correlates with clinical measures of myocardial infarction. J Am Coll Cardiol. 43(12): p. 2253-9.
9. Ishida, N. et al, (2003) Noninfarcted myocardium: correlation between dynamic first-pass contrast-enhanced myocardial MR imaging and quantitative coronary angiography. Radiology. 229(1): p. 209-16.
10. Kim, R. J. et al, (2000) The use of contrast-enhanced magnetic resonance imaging to identify reversible myocardial dysfunction. N Engl J Med. 343(20): p. 1445-53.
11. Kitagawa, K. et al, (2003) Acute myocardial infarction: myocardial viability assessment in patients early thereafter comparison of contrast-enhanced MR imaging with resting (201)Tl SPECT. Single photon emission computed tomography. Radiology. 226(1): p. 138-44.
12 Klein, C. et al., (2008) Combined magnetic resonance coronary artery imaging, myocardial perfusion and late gadolinium enhancement in patients with suspected coronary artery disease. J Cardiovasc Magn Reson. 10: p. 45.
13. Lund, G. K. et al., (2007) Prediction of left ventricular remodeling and analysis of infarct resorption in patients with reperfused myocardial infarcts by using contrast-enhanced MR imaging. Radiology. 245(1): p. 95-102.
14. Ricciardi, M. J. et al., (2001) Visualization of discrete microinfarction after percutaneous coronary intervention associated with mild creatine kinase-MB elevation. Circulation. 103(23): p. 2780-3
15. Tarantini, G. et al, (2006) Influence of transmurality, infarct size, and severe microvascular obstruction on left ventricular remodeling and function after primary coronary angioplasty. Am J Cardiol. 98(8): p. 1033-40.