Cardiac Magnetic Resonance Imaging in diagnose Ischemia Heart Disease

Le Thi Thuy Lien1, Nguyen Khoi Viet1, Nguyen Ngoc Trang1, Pham Minh Thong1,
1 Department of Diagnostic Imaging, Bach Mai Hospital

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Abstract

SUMMARY


Objective: Accuracy of Cardiac Magnetic Resonance in diagnose ischemia heart disease with patients suspected coronary
artery disease (CAD) in comparison to invasive angiography. Material and Methods: Thirty-five patients (61.54±11.23
years, 27 men, 71.4% CAD) underwent CMR including cine, short axis to evaluate EF, EDV, ESV, stress PERF (adenosine 140 μg/
min/kg), rest PERF (SSFP, 3 short axis, 1 saturation prepulse per slice) and LGE (3D inversion recovery technique) using GdBOPTA. Images were analyzed visually. Stenosis >50% in invasive angiography was considered significant.
Results: Mean study time was: 41.37±11.04 minutes, EF: 48.95±18.55%, Hypokinesia: 57.1%, Akinesia: 17.1%. Sensitivity
for PERF, LGE and the combination of PERF/LGE was 100%, 82.4%, 100%, respectively and specificity 80%, 80%, 80%,
respectively. PPV: 94.4%, 93.3%, 94.4%, NPV: 100%, 57.1%, 100%. A good relation (p<0.01) between deficit perfusion state,
the levels of myocardial delayed enhancement correlation with coronary stenosis of LAD, RCA, LCx.
Conclusion: In patients with CAD, the combination of stress PERF, LGE is feasible. A combined perfusion and infarction CMR
examination with can diagnose CAD in the clinical setting. The combination is superior to perfusion-CMR alone.

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References

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