Evaluation value of combined mamography and ultrasound in diagnosis of breast cancer in women under 40 years old
Main Article Content
Abstract
SUMMARY
Purpose: Evaluate value of combined mammography and ultrasound in diagnosis of breast cancer in women under 40 years old.
Material and method: Performed in 122 women under 40 years old, from May 2012 to September 2013 at Bach Mai
hospital and Oncology hospital. Writen records were reviewed for mammography and ultrasound with BI-RADS assessment and histological results. We calculated the sensitivity, specificity and accuracy of mammography and ultrasound with mammography or ultrasound invidual and combined these methods with the gold standand of pathological results.
Result: Among 122 patients, there are 69 primary breast cancer patients and 53 benign mass patients. The sensitivity,
specificity and accuracy of mammography were: 72,5%; 94,3%; 81,9%. The sensitivity, specificity and accuracy of ultrasonography were: 81,2%; 81,1%; 81,1%. The sensitivity, specificity and accuracy of combine of mammography and ultrasonography were: 91,3%; 79,2%; 86,1%.
Conclusion: The combine of mammography and ultrasonography provide a high diagnostic breast cancer in women younger under 40 years old.
Article Details
Keywords
Breast cancer, ultrasound, mammography
References
1. GLOBOCAN. Breast cancer incidence and mortality world wide in 2008. 2008; Available from: http://globocan.iarc.fr/factsheet.asp.
2. Đỗ Doãn Thuận, Nghiên cứu giá trị của chụp X-quang và siêu âm trong chẩn đoán ung thư vú. 2008, Trường Đại học Y Hà Nội: Hà Nội.
3. Lehman, C.D., et al., Accuracy and value of breast ultrasound for primary imaging evaluation of symptomatic women 30-39 years of age. AJR Am J Roentgenol, 2012. 199(5): p. 1169-77.
4. Hindle, W.H., L. Davis, and D. Wright, Clinical value of mammography for symptomatic women 35 years of age and younger. Am J Obstet Gynecol, 1999. 180(6 Pt 1): p. 1484-90.
5. Foxcroft, L.M., E.B. Evans, and A.J. Porter, The diagnosis of breast cancer in women younger than 40. Breast, 2004. 13(4): p. 297-306.
6. Kolb, T.M., J. Lichy, and J.H. Newhouse, Comparison of the performance of screening mammography, physical examination, and breast US and evaluation of factors that influence them: an analysis of 27,825 patient evaluations. Radiology, 2002. 225(1): p. 165-75.
7. Houssami, N., et al., Sydney Breast Imaging Accuracy Study: Comparative sensitivity and specificity of mammography and sonography in young women with symptoms. AJR Am J Roentgenol, 2003. 180(4): p. 935-40.
8. Skaane, P. and A. Skjennald, Screen-film mammography versus full-field digital mammography with soft-copy reading: randomized trial in a populationbased screening program--the Oslo II Study. Radiology, 2004. 232(1): p. 197-204.
9. Jeffries, D.O. and D.D. Adler, Mammographic detection of breast cancer in women under the age of 35. Invest Radiol, 1990. 25(1): p. 67-71.
10. Gewefel, H. and D. Salama, The Accuracy of Combined Mammography and Breast Ultrasound Over Ultrasound Alone in Young Women Below 40 Years. Ultrasound in medicine & biology, 2013. 39(5): p. S40-S41.
11. Corsetti, V., et al., Breast screening with ultrasound in women with mammography-negative dense breasts: evidence on incremental cancer
detection and false positives, and associated cost. Eur J Cancer, 2008. 44(4): p. 539-44.