Article Sidebar
Views PDF: 48
Several factors related to occlusion of brain arteriovenous malformations after treatment by Gamma Knife
Main Article Content
Abstract
SUMMARY
Occlusion rate of cerebral arteriovenous malformations (AVMs) by Gamma Knife Surgery (GKS) is very variaty depending
on the study, may be due to the influence of the structural vascular elements of AVMs, its location, hemorrhage manifestation and
follow-up time post-GKS.
From 2010 to 2014, we had 48 patients who were treated with GKS alone, these patients were diagnosed before and after GKS by images (MSCT and / or MRI and / or angiography). The analyzed factors included: location of nidus (deeply or superficial area), the maximum size of dinus (> 20 mm and ≤ 20 mm), cerebral hemorrhage before treatment (yes, no), Spetzler - Martin (level 1 and level 2-5), follow-up imaging (≤ 24 months and > 24
months). Ratio of occlusion of volume nidus were calculated. Univariate and multivariate analysis to find the elements related
with occlusion AVMs.
Rate occlusion > 75% of the volume occupied by 54.2% (26/48), none of AVMs had done complete occlusion. Results of the study showed that favorable factors for high occlusion were: follow-up time post-radiation surgery, small nidus and low Spetzler - Martin before treatment (p <0.05).
Article Details
Keywords
cerebral arteriovenous malformations, gamma knife surgery
References
1. Trần Đức Thái (2008), Điều trị dị dạng động tĩnh mạch não bằng dao Gamma tại Bệnh viện Đại học Y Dược Huế, Y học thực hành số 635+636, Bộ Y tế xuất bản, tr. 315 – 324
2. Douglas JG, Goodkin R, (2008), Treatment of arteriovenous malformations using Gamma Knife
surgery: the experience at the University of Washington from 2000 to 2005, J Neurosurg (Suppl) 109, pp. 51 – 56.
3. Koltz LT, Polifka AJ, Saltos A (2013), Long-term outcome of Gamma Knife stereotactic radiosurgery for arteriovenous malformations graded by the Spetzler- Martin classification” J Neurosurg 118, pp. 74–83.
4. Shin M, Maruyama K, Kawamoto S, Tago M, (2004), Analysis of nidus obliteration rates after gamma knife surgery for arteriovenous malformations based on long – term follow-up data: the University of Tokyo experience, J Neurosurg 101, pp. 18–24.
5. Zhou D, Liu Z, Yu X, Qi S, Du J (2000), Rotating Gamma System Radiosurgery for Cerebral Arteriovenous Malformations. Stereotact Funct Neurosurg 75:109–116.
6. Inou HK, (2006), Long-term results of Gamma Knife surgery for arteriovenous malformations, 0 to 15-
year follow up in patients treated with lower doses: J Neurosurg (Suppl) 105, pp. 64–68.
7. Shin M, Maruyama K, Kawamoto S, Tago M, (2004), Analysis of nidus obliteration rates after gamma knife surgery for arteriovenous malformations based on long – term follow-up data: the University of Tokyo experience, J Neurosurg 101, pp. 18–24.