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Date Published: 11/07/2022
Online Published: 11/07/2022
Abstract Views: 261
Views PDF: 442
DOI: https://doi.org/10.55046/vjrnm.23.434.2016
Issue
No. 23 (2016)
Section
Scientific research
How to Cite
Nguyen, V. K., Le, V. P., & Trinh, L. H. M. (2022). The value of diffusion-weighted imaging in the detection of prostate cancer. Vietnamese Journal of Radiology and Nuclear Medicine, 23, 38-42. https://doi.org/10.55046/vjrnm.23.434.2016

The value of diffusion-weighted imaging in the detection of prostate cancer

Nguyen Van Khoi1, Le Van Phuoc1, Trinh Le Hong Minh2,
1 Cho Ray Hospital
2 Cho Ray hospital

Main Article Content

Abstract

SUMMARY


Purpose: The aim of study was to determine the value of DWI in diagnosis of prostate carcinoma especially for differentiating
benign from malignant lesion of the prostate.
Materials and methods: During a period of 4/2014-3/2015, 41 consecutive patients with elevated PSA level were evaluated
with DWI of the prostate. The results were confirmed by TRUSguided biopsy. We compare two groups (prostate carcinoma/PCa
and prostate non-carcinoma/PNCa) by variants: tissue diffusivity, mean of ADC… Analyzing ROC curve to find the value of DWI in differentiating benign from malignant tissue of the prostate.
Results: Patients ranged in age from 50 to 94 years (mean 73±10year). 18 patients were confirmed to have PNCa (44%),
whereas 23 patients had Pca (56%). The mean of ADC values for PNCa and PCa were 829.2±119.2 and 544.6±102.7x10-3 mm2/s
respectively. The mean ADC value of PCa was significantly lower than PNCa (p<0.05). On ROC curve, using the discrimination
threshold of ADC is 633x10-3 mm2/s, the DWI provided a sensitivityof 82.6%, specificity of 94.4% and accuracy of 96%.
Conclusions: Diffusion-weighted imaging of the prostate can be used to differentiate benign from malignant tissue of the prostate with high accuracy

Article Details

Keywords

Prostatic carcinoma, non-carcinoma, diffusion magnetic resonance imaging, ADC, TRUS

References

TÀI LIỆU THAM KHẢO
1. Anwar. SS.(2014). Assessment of apparent diffusion coefficient values as predictor of aggressiveness
in peripheral zone prostate cancer: comparison with Gleason score. ISRN Radiol, pp. 263417.
2. Borislav Spajic (2007). The Incidence of Hyperechoic Prostate Cancer in Transrectal Ultrasound– Guided Biopsy Specimens, Urology, 70 (4), pp.734–737
3. Guglielmo Manenti (2014). DWI of Prostate Cancer: Optimal -Value in Clinical Practice, Prostate Cancer.
4. Leonardo Kayat Bittencourt (2012). Prostate MRI: diffusion-weighted imaging at 1.5T correlates better with prostatectomy Gleason grades than TRUSguided biopsies in peripheral zone tumours, European Radiology, 22(2), pp 468-475.
5. Riches SF (2015). Multivariate modelling of prostate cancer combining magnetic resonance derived T2, diffusion, dynamic contrast-enhanced and spectroscopic parameters, European Radiology, 25(5), pp.1247-1256
6. Rinaldi D. (2012). Role of diffusion-weighted magnetic resonance imaging in prostate cancer evaluation. Radiol Med, 117(8), pp.1429-40.
7. Selnæs KM (2012). Peripheral zone prostate cancer localization by multiparametric magnetic resonance at 3 T: unbiased cancer identification by matching to histopathology. Invest Radiol,47(11), pp.624-33
8. Yagci A. B. (2011). The value of diffusionweighted MRI for prostate cancer detection and localization. Diagn Interv Radiol, 17(2), pp.130-4