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Date Published: 11/07/2022
Online Published: 11/07/2022
Abstract Views: 193
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DOI: https://doi.org/10.55046/vjrnm.23.434.2016
Issue
No. 23 (2016)
Section
Scientific research
How to Cite
Nguyen, V. K., Le, V. P., & Trinh, L. H. M. (2022). The value of diffusion-weighted imaging in the detection of prostate cancer. Vietnamese Journal of Radiology and Nuclear Medicine, 23, 38-42. https://doi.org/10.55046/vjrnm.23.434.2016

The value of diffusion-weighted imaging in the detection of prostate cancer

Nguyen Van Khoi1, Le Van Phuoc1, Trinh Le Hong Minh2,
1 Cho Ray Hospital
2 Cho Ray hospital

Main Article Content

Abstract

SUMMARY


Purpose: The aim of study was to determine the value of DWI in diagnosis of prostate carcinoma especially for differentiating
benign from malignant lesion of the prostate.
Materials and methods: During a period of 4/2014-3/2015, 41 consecutive patients with elevated PSA level were evaluated
with DWI of the prostate. The results were confirmed by TRUSguided biopsy. We compare two groups (prostate carcinoma/PCa
and prostate non-carcinoma/PNCa) by variants: tissue diffusivity, mean of ADC… Analyzing ROC curve to find the value of DWI in differentiating benign from malignant tissue of the prostate.
Results: Patients ranged in age from 50 to 94 years (mean 73±10year). 18 patients were confirmed to have PNCa (44%),
whereas 23 patients had Pca (56%). The mean of ADC values for PNCa and PCa were 829.2±119.2 and 544.6±102.7x10-3 mm2/s
respectively. The mean ADC value of PCa was significantly lower than PNCa (p<0.05). On ROC curve, using the discrimination
threshold of ADC is 633x10-3 mm2/s, the DWI provided a sensitivityof 82.6%, specificity of 94.4% and accuracy of 96%.
Conclusions: Diffusion-weighted imaging of the prostate can be used to differentiate benign from malignant tissue of the prostate with high accuracy

Article Details

Keywords

Prostatic carcinoma, non-carcinoma, diffusion magnetic resonance imaging, ADC, TRUS

References

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