CHẤT TƯƠNG PHẢN MRI - PRIMOVIST: VAI TRÒ TRONG CHẨN ĐOÁN THƯƠNG TỔN GAN

Abstract

SUMMARY

Purpose: Assessing the role of hepatobiliary - specific MR contrast Agent in the detection and differentiation of benign and malignant focal liver lesions. Maximizing accuracy of imaging in the context of focal liver lesions is paramount in avoiding unnecessary biopsies, which may result in post-procedural complications.
Methods and Materials: Retrospectively evaluated the 200 patients cases, executed hepatic MRI at Medic Medical center wich hepatobiliary - specific MR contrast Agent. From on January 2013 to on January 2016, age range 28 - 72years. The lesion detected in liver: 65 cases HCC, 5 Metastasis, 2 cholangiocarcinoma, 2 Adenoma, 26 FNH, 24 Hemangiomas, 14 Regenerative nodules, 20 cysts, 5 Abscess, 37cases had normal liver. All the patients executed T2WI fatsat, Diffusion
weighted imaging - MRI with three b values (0, 500, 800 sec/mm2) and Dynamic with Primovist contrast media on the Siemens Avanto 1,5T MRI.
Results: In 65cases MRI HCC: 8 cases <1cm; 32 cases 1-2cm; 25 cases >25cm. 26 cases biopsic result: 24 cases HCC (92%), 2 cases cholangiocarcinoma, 39 cases TOCE or
RFA no biopsy. 5 cases metastas detected primary tumor. 2 cases cholangiocarcinoma are right with biopsic result. 2 cases adenoma: 1case biopsic resulted in adenoma, 1 case follow up over 1year. 25 cases hemangiomas with contrast media from peripheral enhancement progressing to centre of lesion; 12 cases regenerative nodules is follow up over 1 year no change in nodule size; 20 cysts are high-signal intensity like fluid - signal on the T2WI, T1WI, Diffusion and no change of intensity is found after contrast injection; in 5 cases abscess: 3 cases recovered from an illness, 2 cases HCC after biopsy.
Conclusion: Magnetic resonance imaging executed with hepatobiliary - specific MR contrast Agent, contributed to detect
the small lesion and differential diagnosis between benign and malignant tumor of the liver.