Role of computed tomography in diagnosing and staging of the renal cell carcinoma

Dr Dang Dinh Hoan1, Dr Tran Duc Quang1, Dr Nguyen Van An1
1 Department of Diagnostic Imaging- Binh Dan Hospital

Main Article Content

Abstract

Background: Early diagnosis and accurate preoperative staging of the renal cell carcinoma are necessary to select the
most appropriate treatment.
Purposes: This study aims to describe the imaging characteristics and define the value of CT in preoperative staging
of renal cell carcinoma.
Subjecs and methods: Retro - and prospective cross section descriptive study of 105 patients in Binh Dan hospital from Dec
2012 to Apr 2015, with histologically verified renal cell carcinoma and using CT preoperatively. Imaging characteristics and staging were made by evaluating imaging obtained and compared with the operative and postoperative histopathologic results.
Results: The most common location was upper 1/3 kidney (32.4%). Tumor size 41-70mm (52.4%) had the highest
percentages. Tumors had constrast enhancement (100%), unsmooth margins (55.2%), intra-tumoral necrosis (91.0%),
calcification (16.2%). Tumor detection in the nephrographic phase were 100%. Tumors had renal sinus fat invasion (34.3%), extension beyond Gerota’s fascia (17,1%); involvements of ipsilateral renal vein (6.7%), inferior vena cava above diaphragm (4,8%) and below diaphragm (5.7%), invasion of ipsilateral adrenal gland (1%), local lymph nodes (13.3%) and distant metastases (5.7%). Tumors had the surgical stages I, II, III, IV and then the mean tumor sizes increased 40.50mm, 63.60mm, 67.58mm, 97.01mm, respectively. The sensitivity, specificity, accuracy, positive predictive value and negative predictive value of CT to evaluate the perinephric fat invasion were 88.52%, 68.18%, 80.0%, 80.0%, 79.41%, respectively. Percentages of CT staging correlating with operative staging was 90%, in which stage I was 100%, stage IV was 91%.


Conclusions: CT is still the principle basis for preoperative staging of renal cell carcinoma.

Article Details

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