Article Sidebar

PDF
Date Published: 11/07/2022
Online Published: 11/07/2022
Abstract Views: 142
Views PDF: 64
DOI: https://doi.org/10.55046/vjrnm.26.463.2016
Issue
No. 26 (2016)
Section
Scientific research
How to Cite
Dang, D. H., Tran, D. Q., & Nguyen, V. A. (2022). Role of computed tomography in diagnosing and staging of the renal cell carcinoma. Vietnamese Journal of Radiology and Nuclear Medicine, 26, 66-72. https://doi.org/10.55046/vjrnm.26.463.2016

Role of computed tomography in diagnosing and staging of the renal cell carcinoma

Dr Dang Dinh Hoan1, Dr Tran Duc Quang1, Dr Nguyen Van An1
1 Department of Diagnostic Imaging- Binh Dan Hospital

Main Article Content

Abstract

Background: Early diagnosis and accurate preoperative staging of the renal cell carcinoma are necessary to select the
most appropriate treatment.
Purposes: This study aims to describe the imaging characteristics and define the value of CT in preoperative staging
of renal cell carcinoma.
Subjecs and methods: Retro - and prospective cross section descriptive study of 105 patients in Binh Dan hospital from Dec
2012 to Apr 2015, with histologically verified renal cell carcinoma and using CT preoperatively. Imaging characteristics and staging were made by evaluating imaging obtained and compared with the operative and postoperative histopathologic results.
Results: The most common location was upper 1/3 kidney (32.4%). Tumor size 41-70mm (52.4%) had the highest
percentages. Tumors had constrast enhancement (100%), unsmooth margins (55.2%), intra-tumoral necrosis (91.0%),
calcification (16.2%). Tumor detection in the nephrographic phase were 100%. Tumors had renal sinus fat invasion (34.3%), extension beyond Gerota’s fascia (17,1%); involvements of ipsilateral renal vein (6.7%), inferior vena cava above diaphragm (4,8%) and below diaphragm (5.7%), invasion of ipsilateral adrenal gland (1%), local lymph nodes (13.3%) and distant metastases (5.7%). Tumors had the surgical stages I, II, III, IV and then the mean tumor sizes increased 40.50mm, 63.60mm, 67.58mm, 97.01mm, respectively. The sensitivity, specificity, accuracy, positive predictive value and negative predictive value of CT to evaluate the perinephric fat invasion were 88.52%, 68.18%, 80.0%, 80.0%, 79.41%, respectively. Percentages of CT staging correlating with operative staging was 90%, in which stage I was 100%, stage IV was 91%.


Conclusions: CT is still the principle basis for preoperative staging of renal cell carcinoma.

Article Details

Keywords

Computed tomography (CT), renal cell carcinoma.

References

1. Allam M. N et al (2010). “Preoperative staging of renal cell carcinoma using triphasic helical computed tomography”. Egyptian journal of radiology and Nuclear medicine. Elsevier, 41, pp 421-428.
2. Angthong W. et al (2010). Accuracy of multidetector CT scan in preoperative staging of renal cell carcinoma: Comparison of radiological and histopathological findings. Siriraj Med J, 62 (1), pp. 18-22.
3. Baert AL., Sartor K. (2006). Imaging of renal cancer. Springer. German. pp. 103-125.
4. Haaga JR. et al (2008), CT and MRI of the whole body, Mosby, pp.1863-1943.
5. Kadhim M. et al (2009). Preoperative staging of renal cell carcinoma: Spiral CT versus pathological considerations. Iraq J Med Sci, 8 (4), pp. 19-27.
6. Kim Ch. et al (2014). Diagnotic value of multidetector computed tomography for renal sinus invasion in renal cell carcinoma patients. European
journal of radiology, 83 (6), pp. 914 -918.
7. Kim KK. et al (2009). Diagnotic performance of multidetector row CT for predicting the preoperative staging of renal cell carcinoma. J Korean Soc Radiol, 60, pp. 109-116.
8. Lim D. J. et al (1993). Computed tomography in the preoperative staging for pulmonary metastases in patients with renal cell carcinoma.J urol, 150 (4), pp. 1112-4.
9. Liu Y et al (2012). “The accuracy of multidetector computed tomography for preoperative staging of renal cell carcinoma”. Int BrazJ urol, 38 (5), pp 627-36.
10. Masuda F. et al (1989). Accuracy of computed tomtography in the staging of renal cell carcinoma. Japanese Jour of Urology, 80 (2), pp. 192-196.
11. Nazim S. M. et al (2011). Accuracy of multidetector CT scans in staging of renal carcinoma. International journal of Surgery. Elsevier, 9, pp. 86-90.
12. Nguyễn Việt Dũng, Nguyễn Văn Hiếu (2008). “Vai trò của chụp cắt lớp vi tính trong chẩn đoán mức xâm lấn ung thư tế bào thận”. Y học TP. Hồ Chí Minh, tập 12 (4), tr. 110-115.
13. Nguyễn Minh Đức (2012). “Khảo sát đặc điểm hình ảnh CLĐT carcinoma tế bào thận”. Y học TP. Hồ Chí Minh, tập 16 (1), tr. 25-26.
14. Nguyễn Trường Giang (2008). Luận văn thạc sỹ: Nghiên cứu đặc điểm hình thái học ung thư biểu mô tế bào thận ở người lớn. Đại học Y Hà Nội.
15. Trần Anh Tú và Cs (2004). “29 đặc điểm ung thư tế bào thận trên CT Scan ở Bệnh Viện Bình Dân”. Y học TP. Hồ Chí Minh, tập 8, phụ bản số 1, tr. 197-205.
16. Raman SP. et al (2013). Chromophobe renal cell carcinoma: Multiphase MDCT enhancement patterns and morphologic features. AJR, 201, pp. 1268-1276.
17. Sureka B. et al (2014). Dynamic computed tomography and doppler findings in differrent subtypes of renal cell carcinoma with their istological correlation. Journal of cancer research and therapeutics, 10 (3), pp. 552-557.
18. Turkvatan A. et al (2009). Preoperative staging of renal cell carcinoma with multidetector CT. Diagn Interv Radiol, 15, pp. 22-30.
19. Wein NJ et al (2007). Campbell-Walsh urology. Elsevier. Philadelphia, pp 520-553.