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Date Published: 08/07/2022
Online Published: 08/07/2022
Abstract Views: 145
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DOI: https://doi.org/10.55046/vjrnm.34.579.2019
Issue
No. 34 (2019)
Section
Scientific research
How to Cite
Nguyen, H. H., Nguyen, Q. T., Nguyen, T. K. D., & Le, N. H. (2022). The relationships between suvmax and morphologic features of bone metastatic lesions on 99mtc-mdp spect/ct in known cancer patients. Vietnamese Journal of Radiology and Nuclear Medicine, 34, 54-60. https://doi.org/10.55046/vjrnm.34.579.2019

The relationships between suvmax and morphologic features of bone metastatic lesions on 99mtc-mdp spect/ct in known cancer patients

Nguyen Hai Hoang1, Nguyen Quang Trung1, Nguyen Thi Kim Dung2, Le Ngoc Ha2,
1 Nghe An Oncology Hospital
2 Military Central Hospital 108

Main Article Content

Abstract

SUMMARY


The aim of our study was to evaluate the relationships between SUVmax and morphologic features of bone metastasis on 99mTc-MDP
SPECT/CT in known cancer patients.
Materials and Methods: This prospective study enrolled 90 known cancer patients (32 women and 58 men patients with aged average of 61.6
± 10.4) underwent 99mTc-MDP SPECT/CT scans from February 2018 to February 2019 at Nuclear Medicine Department, 108 central military hospital. Bone metastatic lesions were classified based on morphologic features on CT. The standadized uptake values (SUVmax) were measured at each morphologic features of bone metastasis and determining the relationships
between SUVmax and those lesions in different primary cancer diseases.
Results: The total of 264 lesions were found in 90 patients. Of which, 29% was osteolytic, 25% was osteoblastic, 23% was mixed and 23% was
unclassified lesions on CT. SUVmax values at osteolytic lesions were significantly lower than other types of lesions (p<0.05). SUVmax values of
bone lesions in thyroid cancer, liver cancer patients were lower compared to those in prostate cancer and lung cancer patients. This difference was statistically significant (p<0.05).
Conclusions: The morphologic features of bone metastatic lesions on CT were found to be in correlation to metabolic bone changes on 99mTc-
MDP SPECT/CT imaging.

Article Details

Keywords

SPECT/CT, bone metastasis, SUVmax

References

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