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Assessment of left ventricular dyssynchrony by SPECT myocardial perfusion imaging in post myocardial infartion patients
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Abstract
SUMMARY
Objective: to evaluate left ventricular synchrony parameters using gated myocardial perfusion single photon emission computed tomography
(GSPECT) in post myocardial infarction (MI) patients.
Subject and methods: a cross - sectional study was conducted on 34 subjects without cardiovascular disease and 104 post-MI patients.
Results: left ventricular dyssynchrony parameters including PSD and HBW were 48.7 ± 19.49 and 154.95 ± 71.97 in post-MI group compared to
17.5 ± 7.24 and 53.9 ± 15.14 respectively in control group (p<0.01). 77% and 81% of post-MI patients had increased PSD and HBW with left ventricular dyssynchrony. PSD and HBW has increased significantly in post-MI patients
with NYHA III-V, low EF compared to NYHA I-II patient group without left ventricular dysfunction.
Conclusion: left ventricular dyssynchrony parameters were commonly detected by gated SPECT in post-MI patients. PSD and HBW increased significantly in post-MI patients and had relationships to NYHA and left ventricular dysfunction.
Article Details
Keywords
myocardial perfusion imaging, left ventricular dyssynchrony, myocardial infarction
References
1. Quyền Đăng Tuyên (2010), Nghiên cứu rối loạn đồng bộ tâm thất ở bệnh nhân suy tim bằng siêu âm Doppler và Dopller mô cơ tim, Luận án tiến sĩ y học, Viện Nghiên cứu khoa học y dược lâm sàng 108.
2. Vũ Thị Phương Lan (2012), Nghiên cứu đặc điểm và giá trị tiên lượng của xạ hình tưới máu cơ tim ở bệnh nhân sau nhồi máu cơ tim, Luận án tiến sĩ Y học, Viện nghiên cứu y dược học lâm sàng 108.
3. Ng A.C.T, Tran D.T., Allman C., et al. (2010), Prognostic implications of left ventricular dyssynchrony early after
non-ST elevation myocardial infarction without congestive heart failure, Eur Heart J, 31(3), pp. 298-308.
4. Ko J.S., Jeong M.H., Lee M.G., et al. (2009), Left Ventricular Dyssynchrony After Acute Myocardial Infarction is a Powerful Indicator of Left Ventricular Remodeling, Korean Circ J, 39(6), pp. 236-42.
5. Pazhenkottil, Aju P, Buechel, Ronny R, and Husmann, Lars (2011), “Long-term prognostic value of left ventricular
dyssynchrony assessment by phase analysis from myocardial perfusion imaging”, Heart. 97, pp. 33-37.
6. Holly, Thomas A., Abbott, Brian G., and Al-Mallah, Mouaz (2010), “ASNC IMAGING GUIDELINES FOR NUCLEAR CARDIOLOGY PROCEDURES: Single photon-emission computed tomography”, Journal of Nuclear Cardiology. 17(5), pp. 941-973.
7. Chen, Ji, Garcia, Ernest V., and Bax, Jeroen J. (2011), “SPECT myocardial perfusion imaging for the assessment of left ventricular mechanical dyssynchrony”, Journal of Nuclear Cardiology. 18(4), pp. 685-694.
8. Chen, Ji, Garcia, Ernest V., and Folks, Russell D. (2005), “Onset of left ventricular mechanical contraction as determined by phase analysis of ECG-gated myocardial perfusion SPECT imaging: Development of a diagnostic tool for assessment of cardiac mechanical dyssynchrony”, Journal of Nuclear Cardiology. 12(6), pp. 687-695.
9. Alam I., Haque T., Badiuzzaman M., et al. (2016), Left Ventricular Dyssynchrony in Acute ST Elevated Myocardial Infarction in Patients with Normal QRS duration, Bangladesh Heart Journal, 30(1), pp. 13-21.
10. Henneman M.M., Chen J., Dibbets-Schneider P., et al. (2007), Can LV dyssynchrony as assessed with phase analysis on gated myocardial perfusion SPECT predict response to CRT?, J Nucl Med, 48(7), pp. 1104-11.
11. Zafrir N., Nevzorov R., Bental T., et al. (2014), Prognostic value of left ventricular dyssynchrony by myocardial perfusiongated SPECT in patients with normal and abnormal left ventricular functions, J Nucl Cardiol, 21(3), pp. 532-40.
12. Fudim M., Fathallah M., Shaw L.K., et al. (2018), The Prognostic Value of Diastolic and Systolic Mechanical Left Ventricular Dyssynchrony Among Patients With Coronary Heart Disease, JACC Cardiovasc Imaging.