Research value of ultrasonographic features suggests malignancy of the thyroid nodules

Pham Thi Khanh Le1, Nguyen Phuoc Bao Quan1,
1 Hue University of Medicine and Pharmacy, Hue central hospital

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Abstract

SUMMARY


Purposes: Describe imaging characteristics and assess
value of ultrasonographic features suggests malignancy of the thyroid nodules.
Materials and methods: There are 263 consecutive patients with thyroid nodules on ultrasound. All of them were undergone operation with pathology after surgery.
Results: The average age is 63 years old, and female/
male=10/1. Histopathology results after surgery, thyroid cancer. The solitary nodules are the highest ratio (65.8%). Most lesions are over 20 mm in size (74.2%). Most patients with solid nodules (50.6%) and the rate of malignant lesions in this group also had the highest (17.3%). The lesions with marked hypoechogenicity, microcalcifications, an irregular or microlobulated margin, a shape that was more tall than it was wide and marked internal vascularityhave lower proportion (11.2%, 9.1%, 9.5%, 6.1% and 5.7%), but the rate of malignant lesions in these group are over 50%. Thefeaturewith the highest sensitivity is solid composition (95.8%). Microcalcifications, irregular or microlobulated margin, a shape that was more tall than it was wide and marked internal vascularity have high specificity (95.8% - 97.1%). The featurewith the highest positive predictive valueis the presence of microcalcifications (66.7%).
Conclusion: The ultrasonographic features suggests malignancy have high value: marked hypoechogenicity, microcalcificationsand an irregular or microlobulated margin.

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References

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