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Diagnostic performance of stress perfusion cardiovascular magnetic resonance for detection of Ischemia Heart Disease
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Abstract
SUMMARY
Objective: Evaluation of the diagnostic of stress perfusion
cardiovascular magnetic resonance for the diagnosis of significant obstructive coronary artery disease in comparison to invasive coronary angiography.
Material and Methods: 36 patients with suspected ischemic heart disease/ 25 males (69.4%) with mean age: 65.53 ± 10.48 year underwent 1.5 Tesla CMR including cine, short axis to evaluate EF, EDV, ESV, stress PERF (adenosine 140 μg/min/kg), rest PERF (SSFP, 3 short axis, 1 saturation prepulse per slice) and LGE (3D inversion recovery technique) using Gd-BOPTA. Images were analyzed visually. Stenosis >50% in invasive angiography
was considered significant.
Results: Mean study time was: 45.44 ± 9.18 minutes, EF:
45.06 ± 15.66%, Hypokinesia: 44.4%, Akinesia: 27.8%. The overall patient-based analysis demonstrated a high sensitivity, specificity and PPV for perfusion was 93.3%; 83.3%; 96.6% and moderate NPV 71.4%. A good relation (p<0.01) between deficit perfusion state correlation with coronary stenosis of LAD, RCA, LCx.
Conclusion: Stress perfusion CMR with Adenosine is highly
sensitive and specificity for detection of coronary artery disease.
Article Details
Keywords
Cardiac Magnetic Resonace (CMR), diagnose, coronary artery disease, ischemia heart disease (IHD), coronary artery, perfusion, Adenosine
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