Evalutating the role of ct scanncer in track of colon carcinomawith chemical treatment after surgery

Van Thi Tho1, Bui Van Lenh2,
1 National Institute of Malaria - Parasites - Insects
2 Hanoi Medical University Hospital

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Abstract

SUMMARY


Objectives: 1) Describe the CT scanner imaginary feature of some common metastases of colon carcinoma; 2) Evaluate the role of CT scanner in tracking colon carcinoma during chemical treatment after surgery.
Materials and methods: Study of comparative description 40 patients getting the diagnosis determined colon carcinoma after tumor cutting surgery, get treated by Oxaliplatin and supplement, CT scanner periodic checks at Hanoi Medical University Hospital.
Results: Common metastatic colon carcinoma are Node
metastase and Distant metastase. Node metastasis occured with the rate of 17.5%, mainly distributed in ganglion location, no nodes were found in edge of the colon. The nodes are short-axis diameter ≥ 10mm. Distant metastases occured in the liver organ (20%), often circular,
with many cecidiums of diverse diameter: 8 patients having liver metastases with 28 cecidiums, most popular with 4 patients having 5 liver metastases cecidiums and all > 10mm. There are 24 cecidiums >10mm is characterized by reducing the density after infiltration injection of drugs around; Peritoneal metastasis occur 15%. Besides there are Ovaries metastase and bone metastases. The number of metastatic is almost descending through checks with CT scanner from 24 patients (60%) before treatment to 20 patients (50%) after 3 chemical cycles and 3 patients (7.5%) after 6 chemical cycles. Only 1 cecidium in ganglion position exist with size ≥15mm. In addition, the size of metastatic lesions as well as the amount of fluid in peritoneal also reduced after the treatment, the largest decline after 6 chemical cycles. The density and drug absorbability also change the morphology upon the response of chemical treatment; treating liver metastases helps shrink the size<10mm, especially with a diameter <5 mm, the cecidium metastasis before injection reduces the density and absorb drug steadily and late. Some peritoneal metastatic cecidiums also become when meeting the treatment and unchanged through checks.
Conclusion: CT scanner is able to allocate some types of
metastases of colon carcinoma on location, size, amount, intensity and drug infusibility of metastases over treatment periodic checks.

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References

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