High resolution magnetic resonance imaging of retinoblastoma

Hoang Dang Tuan1,, Pham Hong Duc2, Dinh Trung Thanh2
1 Đại học Y Hà Nội
2 Saint Paul general hospital

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Abstract

Purpose: To describe the imaging characterization of high-resolution magnetic resonance imaging of retinoblastoma


Material  and  method:  About 50 patients were diagnosed and monitored for retinoblastoma treatment at the National Eye Hospital and performed 3T magnetic resonance at Saint Paul General Hospital from October 2020 to May 2022. Description of tumor intraocular lesion: Number, location of tumor, largest diameter. Description of tumor characteristics: Signals on sequences T1W, T2W, FLAIR, DWI and enhancement properties after injection. Other accompanying features: Intra-tumor calcification, retinal detachment, vitreous hemorrhage, optic nerve invasion, invasion outside the eyeball, intracranial lesions


Results: 50 patients in the study had an average age of 21.2 months, and the age of the one-eye disease group was higher than that of the two-eyed disease group. 3T MRI is a good method for diagnosing retinoblastoma tumors, with the largest dimension measuring 13.8 ± 4.2 mm, the tumor distribution is mainly on the retina in the post-equatorial region. Tumor image on MRI compared with vitreous signal, mostly increased signal on T1W (92.6%), decreased on T2W (98.8%), increased on FLAIR (100%), restriction on DWI (100%) and enhancement after injection. Signs of calcification are specific for retinoblastoma, however, on MRI the ability to detect calcification is limited. Although the detection of calcification is limited, it has good ability in invasive assessment such as choroidal invasion (15.6%), scleral invasion (3.1%), optic nerve invasion (31.3). %). Severe prognostic signs such as retinal detachment (34.4%), vitreous bleeding (26.6%).


Conclusion: 3T magnetic resonance is a good method of diagnosing retinoblastomas as well as assessing the invasiveness of tumors.

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References

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