THE LUNG POINT: AN ULTRASOUND FINDING IN THE DIAGNOSIS AND SEMI-QUANTIFICATION OF PNEUMOTHORAX AFTER CT-GUIDED TRANSTHORACIC BIOPSY

Ngọc Mai Thị1,, Dam Thuy Trang2, Nguyen Thi Thu Thao2, Nguyen Thi Khoi3, Nguyen Thanh Thuy4, Nguyen Phuong Anh4, Vu Dang Luu4
1 Bệnh Viện Bạch Mai
2 2Radiology Center, Bach Mai Hospital
3 Radiology Center, Bach Mai Hospital
4 Radiology Center - Bach Mai Hospital

Main Article Content

Abstract

This study focused on evaluating the diagnostic performance of the lung point (LP)- a lung ultrasound (LUS) sign in detecting and semi-quantifying pneumothorax (PTX), using computed tomography (CT) as the reference standard. The study included 150 patients who underwent CT-guided transthoracic biopsy (TTB) for lung lesions. Two radiologists blinded to the participant’s prior information performed LUS post-biopsy. The results showed that PTX was present on CT in 49/150 (32.3%) cases. The LP was positive in 36/150 (24%) patients, with a substantial agreement between the two radiologists (Cohen κ statistics = 0.8). The sensitivity and specificity of the LP were 73.5% (95%CI 66.5% to 80.5) and 100% (95%CI 97.6% to 100%), respectively. Moreover, the positive and negative predictive values were 100% (95%CI 97.6% to 100%) and 67.3% (95%CI 59.8% to 78.4%), respectively. In the semi-quantification of PTX, the location of LP was described in 36/49 (73.5%) patients. The sensitivity and specificity of this sign were 87.5% (95%CI 82.2% to 92.8%) and 96.4% (95%CI 92.4% to 98.9%), respectively. The positive and negative predictive values were 87.5% (95%CI 82.2% to 92.8%) and 96.4% (95%CI 92.4% to 98.9%), respectively. In conclusion, LP is a susceptible and specific LUS sign for diagnosing and semi-quantifying PTX.

Article Details

References

1. Morello FA, Wright KC, Lembo TM. New suction guide needle designed to reduce the incidence of biopsyrelated pneumothorax: experimental evaluation in canine model. Radiology. 2005;235(3):1045-1049. doi:10.1148/radiol.2353040433
2. Heerink WJ, de Bock GH, de Jonge GJ, Groen HJM, Vliegenthart R, Oudkerk M. Complication rates of CT-guided transthoracic lung biopsy: meta-analysis. Eur Radiol. 2017;27(1):138-148. doi:10.1007/s00330-016-4357-8
3. Abdulrahman Y, Musthafa S, Hakim SY, et al. Utility of extended FAST in blunt chest trauma: is it the time to be used in the ATLS algorithm? World J Surg. 2015;39(1):172-178. doi:10.1007/s00268-014-2781-y
4. Soult MC, Weireter LJ, Britt RC, et al. Can routine trauma bay chest x-ray be bypassed with an extended focused assessment with sonography for trauma examination? Am Surg. 2015;81(4):336-340.
5. Chan KK, Joo DA, McRae AD, et al. Chest ultrasonography versus supine chest radiography for diagnosis of pneumothorax in trauma patients in the emergency department. Cochrane Database Syst Rev. 2020;7:CD013031. doi:10.1002/14651858.CD013031.pub2
6. Volpicelli G, Boero E, Sverzellati N, et al. Semi-quantification of pneumothorax volume by lung ultrasound. Intensive Care Med. 2014;40(10):1460-1467. doi:10.1007/s00134-014-3402-9
7. Hosseini-Nik H, Bayanati H, Souza CA, et al. Limited Chest Ultrasound to Replace CXR in Diagnosis of Pneumothorax Post Image-Guided Transthoracic Interventions. Can Assoc Radiol J. 2022;73(2):403-409. doi:10.1177/08465371211034016
8. Mayo PH, Beaulieu Y, Doelken P, et al. American College of Chest Physicians/La Société de Réanimation de Langue Française statement on competence in critical care ultrasonography. Chest. 2009;135(4):1050-1060. doi:10.1378/chest.08-2305
9. MacDuff A, Arnold A, Harvey J, on behalf of the BTS Pleural Disease Guideline Group. Management of spontaneous pneumothorax: British Thoracic Society pleural disease guideline 2010. Thorax. 2010;65(Suppl 2):ii18-ii31. doi:10.1136/thx.2010.136986
10. Lichtenstein DA, Mezière G, Lascols N, et al. Ultrasound diagnosis of occult pneumothorax. Crit Care Med. 2005;33(6):1231-1238. doi:10.1097/01.ccm.0000164542.86954.b4
11. Lichtenstein DA. BLUE-Protocol and FALLS-Protocol. Chest. 2015;147(6):1659-1670. doi:10.1378/chest.14-1313
12. Lung Ultrasound Made Easy: Step-By-Step Guide. POCUS 101. Accessed October 4, 2022. https://www.pocus101. com/lung-ultrasound-made-easy-step-by-step-guide/
13. Lichtenstein D, Mezière G, Biderman P, Gepner A. The “lung point”: an ultrasound sign specific to pneumothorax. Intensive Care Med. 2000;26(10):1434-1440. doi:10.1007/s001340000627
14. Santos-Silva J, Lichtenstein D, Tuinman PR, Elbers PWG. The lung point, still a sign specific to pneumothorax. Intensive Care Med. 2019;45(9):1327-1328. doi:10.1007/s00134-019-05677-z 15. Steenvoorden TS, Hilderink B, Elbers PWG, Tuinman PR. Lung point in the absence of pneumothorax. Intensive Care Med. 2018;44(8):1329-1330. doi:10.1007/s00134-018-5112-1
16. A physiological sign that mimics lung point in critical care ultrasonography | Critical Care | Full Text. Accessed September 12, 2022. ttps://ccforum.biomedcentral.com/articles/10.1186/s13054-015-0863-3
17. Sartori S, Tombesi P, Trevisani L, Nielsen I, Tassinari D, Abbasciano V. Accuracy of transthoracic sonography in detection of pneumothorax after sonographically guided lung biopsy: prospective comparison with chest radiography. AJR Am J Roentgenol. 2007;188(1):37-41. doi:10.2214/AJR.05.1716