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Date Published: 09/07/2024
Online Published: 31/08/2023
Abstract Views: 73
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DOI: https://doi.org/10.55046/vjrnm.52.910.2023
Issue
No. 52 (2023)
Section
Scientific research
How to Cite
Trần, T. T. T., Tran, D. K., Nguyen , N. T., & Vu, D. L. (2023). Imaging characteristics and the role of whole body multidetector computed tomography in patients with stage IV prostate cancer . Vietnamese Journal of Radiology and Nuclear Medicine, 52, 39-46. https://doi.org/10.55046/vjrnm.52.910.2023

Imaging characteristics and the role of whole body multidetector computed tomography in patients with stage IV prostate cancer

Thị Thanh Thanh Trần1,, Tran Dang Khoa2, Nguyen Ngoc Trang3, Dr Vu Dang Luu4
1 Bệnh viện Hữu Nghị
2 Department of Diagnostic Imaging, Friendship Hospital
3 Dien Quang Center, Bach Mai Hospital
4 Department of Diagnostic Imaging, Hanoi Medical University

Main Article Content

Abstract

Purpose: The study was conducted to characterize image characteristics of prostate cancer on multidetector computed tomography (MDCT) and evaluate the role of MDCT patients with stage IV prostate cancer.


Objectives and subjects: A cross-sectional study was performed on 45 patients at Huu Nghi Hospital from January 2017 to May 2023. All patients were definitively diagnosed with prostate cancer, taken multi-parameter magnetic resonance imaging (mp-MRI), MDCT, bone scan and had stage IV diagnosis after having the above tests.


Results: Study on 45 patients with mean age 78.31±5.64 years, mean Total prostate-specific antigen (tPSA) concentration 279.78 ng/ml, mean prostate volume 45.20 ml. 60% of patients with invasive lesions outside the gland and 66.7% of patients with regional lymph node metastases; 40% of patients with extra-regional lymph node metastasis; 46.7% of patients with bone metastasis; 28.9% of patients with other organs metastasis. MDCT has good to very good concordance with MRI in evaluating local invasive lesions and good concordance with bone scintigraphy in evaluating bone metastasis, with p <0.05.


Conclusion: MDCT has high value in assessing metastatic lesions in patients with stage IV prostate cancer, especially lung lesions. Whole-body MDCT can be used in hospitals that do not have whole-body MRI and PET/CT in evaluating metastatic lesions from prostate cancer.

Article Details

Keywords

Prostate cancer, Multidetector computerized tomography, bone scintigraphy.

References

1. Sung H., Ferlay J., Siegel R. L, et al. Global cancer statistics 2020: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries. CA: a cancer journal for clinicians. 2021;71(3):209-249.
2. Resnick M. J., Koyama T., Fan K. H., et al. Long-term functional outcomes after treatment for localized prostate cancer. N Engl J Med. 2013;368:436-445.
3. Chen W., Zheng R., Baade P. D., et al. Cancer statistics in China, 2015. CA: a cancer journal for clinicians. 2016;66(2):115-132.
4. Mottet N., Bellmunt J., Bolla M., et al. EAU-ESTRO-SIOG guidelines on prostate cancer. Part 1: screening, diagnosis, and local treatment with curative intent. European urology. 2017;71(4):618-629.
5. Schiavina R., Chessa F., Borghesi M., et al. State-of-the-art imaging techniques in the management of preoperative staging and re‐staging of prostate cancer. International Journal of Urology. 2019;26(1):18-30.
6. Pesapane F., Czarniecki M., Suter M. B., et al. Imaging of distant metastases of prostate cancer. Medical Oncology. 2018;35(11):1-17.
7. Rosenkrantz A. (Ed.). MRI of the Prostate: A Practical Approach. Thieme. 2016.
8. Buyyounouski M. K., Choyke P. L., McKenney J. K., et al. Prostate cancer–major changes in the American Joint Committee on Cancer eighth edition cancer staging manual. CA: a cancer journal for clinicians. 2017;67(3):245-253.
9. Gandaglia G., Abdollah F., Schiffmann J., et al. Distribution of metastatic sites in patients with prostate cancer: a population‐based analysis. The Prostate. 2014;74(2):210-216.
10. Lê Thị Khánh Tâm. Đánh giá kết quả điều trị nội tiết ung thư tuyến tiền liệt giai đoạn IV. Luận án Tiến sỹ. Trường Đại học Y Hà Nội; 2020.
11. Bubendorf L., Schöpfer A., Wagner U., et al. Metastatic patterns of prostate cancer: an autopsy study of 1,589 patients. Human Pathology. 2000;31(5):578-583.
12. Engeler C. E., Wasserman N. F., Zhang G. Preoperative assessment of prostatic carcinoma by computerized tomography: Weaknesses and new perspectives. Urology. 1992;40(4):346-350.
13. Tanimoto A., Nakashima J., Kohno H., et al. Prostate cancer screening: the clinical value of diffusion-weighted imaging and dynamic MR imaging in combination with T2-weighted imaging. Journal of Magnetic Resonance Imaging: An Official Journal of the International Society for Magnetic Resonance in Medicine. 2007;25(1):146-152.
14. Zhang J. Computed tomography imaging in patients with prostate cancer. In: Hricak H, Scardino P, eds. Prostate cancer. Cambridge University Press; 2009:120 - 139:chap 8.