NHẬN XÉT ĐẶC ĐIỂM HÌNH ẢNH 18F-FDG PET/CT CỦA U LYMPHO KHÔNG HODGKIN TẾ BÀO B TẠI BỆNH VIỆN UNG BƯỚU HÀ NỘI

Văn Thắng Nguyễn1,, Văn Tuynh Chu, Văn Thái Phạm
1 Khoa YHHN - BV Ung bướu Hà Nội

Main Article Content

Abstract

Objective: This study aimed to review 18F-FDG PET/CT imaging characteristics of B cell Non-Hodgkin’s lymphoma at Hanoi Oncology Hospital.


Materials and Methods: A descriptive study was conducted on 86 newly diagnosed B cell Non Hodgkin’s lymphoma by histopathology and immunohistochemistry at Hanoi Oncology Hospital from January 2018 to December 2022. Those patients undergone 18F-FDG PET/CT scans for pre-treatment staging.


Results: Among 86 B cell NHL patients, 38 female and 48 male with mean age was 58.1. There were 72 patients with aggressive NHL, in which DLBCL accounted for 45.3%. According to PET/CT imaging, the highest frequency lymph nodes were cervical and abdominal lymph nodes with 65.1% and 53.5%, correspondingly. The other lymph nodes were mediastinal (34.9%), axillary (30.2%) and inguinal (22.1%). PET/CT showed 23 extranodal sites/organs, most commonly were tonsil (16.3%), spleen (9.3%), bone marrow (9.3%), stomach (8.1%), nasopharynx (7.0%). The median SUVmax of aggressive NHL was 11.3, indolent NHL was 5.4, p < 0.01. Analysis of the linear correlation between size and SUVmax showed r = 0.547, p< 0.01.


Conclusions: PET/CT helps to detect lesions of B cell NHL at many sites. The SUVmax value are often high and depend on histopathology subtypes. There was a linear relationship between size and SUVmax.


Keywords: B cell Non Hodgkin’s lymphoma, 18F-FDG PET/CT.

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