VAI TRÒ CỦA SINH THIẾT BẰNG KIM LÕI DƯỚI HƯỚNG DẪN SIÊU ÂM TRONG ĐÁNH GIÁ HẠCH CỔ BẤT THƯỜNG

THI HOA VU1,, Vu Thi Thu Lan2, Le Huy Thai2, Nguyen Thi Hang2, Nguyen Viet Ha2
1 Bệnh viện Trung Ương Quân Đội 108
2 Central Military Hospital 108

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Abstract

Objective: To evaluate the effectiveness and factors influencing of ultrasound-guided core needle biopsy (US-CNB). Subjects and Methods: A cross-sectional descriptive study was conducted on 201 patients with suspected cervical lymphadenopathy in clinical practice, having a transverse diameter ≥ 5mm, who underwent US-CNB at the Diagnostic Ultrasound Department of 108 Military Central Hospital from January 2022 to September 2023. Results: A total of 201 suspected cervical lymphadenopathys, metastatic lymph nodes were the majority at 105 cases (52.2%), lymphoma at 32 cases (15.9%), and benign lymph nodes at 64 cases (31.9%). Adequate diagnostic and histopathological subtyping specimens constituted the majority with 126 cases (62.6%), specimens requiring additional testing for diagnosis were 51 cases (25.4%), specimens deemed inadequate were 7 cases (3.5%), and equivocal specimens requiring surgical excision were 17 cases (8.5%). The sensitivity, specificity, and accuracy of cervical lymphadenopathy US-CNB were 93.4%, 100%, and 95.5%, respectively. Among 32 lymphomas, 21 cases were diagnosed through US-CNB, and the remaining 11 cases required surgery, resulting in an overall accuracy of 65.6% for diagnosing lymphoma. Inadequate lymphadenopathy specimens were more common in the lymphoma group compared to metastatic and benign lymph nodes, and this difference was statistically significant with p < 0.05. Differences in transverse diameter, necrotic features, and needle size between the two groups were not statistically significant. No complications were encountered post-US-CNB. Conclusion: US-CNB is a safe and effective method for diagnosing cervical lymphadenopathy with high accuracy and minimal invasiveness

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References

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