The role of computed tomography pulmonary angiography in assessing severity in patients with acute pulmonary embolism

Đoàn Duy Quang Nguyễn1,, Đo Thi Thu Thao2, Tran Thi Mai Thuy3, Le Minh Thang2, Le Nguyen Gia Hy2
1 Bệnh viện Đại Học Y Được TPHCM
2 Department of Diagnostic Imaging, University of Medicine and Pharmacy Hospital, Ho Chi Minh City
3 Department of Diagnostic Imaging, University of Medicine and Pharmacy, Ho Chi Minh City

Main Article Content

Abstract

Objective: To describe the imaging characteristics of PE on CTPA and assess the relationship between CTPA imaging characteristics and the ability to predict severity in PE patients.


Subjects and methods: 112 cases of PE were divided into two groups: high-risk PE (HRPE) and non-high-risk PE (NHRPE), comparing the PESI score and CTPA imaging variables.


Results: The HRPE group had significantly higher PESI score (175.78±39.94), Qanadli score (60.56±21.25), and RVD/LVD ratio (2.39±0.80) compared to the NHRPE group with PESI score (76.60±25.27), Qanadli score (31.75±20.51), and RVD/LVD ratio (1.01±0.29), (P < 0.05). Variables such as RVD, LVD, and interventricular septal abnormalities also showed differences between the two groups (P < 0.05). PAD, AD, PAD/AD ratio, and contrast reflux into the inferior vena cava showed no differences between the two groups (P ≥ 0.05). The RVD/LVD ratio strongly correlated with Qanadli score (r = 0.520) and PESI score (r = 0.510), while Qanadli score weakly correlated with PESI score (r = 0.265). The highest area under the curve for PESI score, reaching 0.998 (95% CI: 0.992-1.000), with a cut-off point of 122.5; RVD/LVD ratio reached 0.981 (95% CI: 0.953-1.000), with a cut-off point of 1.339; Qanadli score reached 0.851 (95% CI: 0.688-1.000), with a cut-off point of 51.339. The RVD/LVD ratio was a predictor of HRPE (P < 0.05).


Conclusion: CTPA imaging is valuable in stratifying the risk of PE, along with the PESI score.


Keywords: Pulmonary embolism, Computed tomography pulmonary angiography, Pulmonary embolism risk stratification.

Article Details

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