NGHIÊN CỨU ĐẶC ĐIỂM HÌNH ẢNH VÀ VAI TRÒ CỦA 18FDG-PET/CT TRONG CHẨN ĐOÁN GIAI ĐOẠN CỦA BỆNH NHÂN UNG THƯ PHỔI KHÔNG TẾ BÀO NHỎ.

Abstract

Objectives: Study on ¹⁸FDG-PET/CT imaging characteristics of lesions in non-small cell lung cancer before treatment and  the role of 18FDG-PET/CT in the staging of patients with non-small cell lung cancer.Methods: Retrospective study, descriptive analysis on 43 non-small cell lung cancer patients who were newly detected taken ¹⁸FDG-PET/CT at Military Hospital 103 from February 2017 to February 2022, including 32 patients were indicated for surgery after ¹⁸FDG-PET/CT scan without any specific treatment.Results: The average size of lung tumor was 40.98±21.53mm, there was a correlation between SUVmax index and primary tumor size. The SUVmax value increased with stage T. The mean SUVmax value of the lymph node group >10mm was 10.59±6.12 higher than that of the node group <10mm was 5.56±2.47. After PET/CT scan, the N0 stage accounted for 32.6%, the N1 stage accounted for 23.3%, the N2 stage accounted for 23.3%, and the N3 stage accounted for 20.9%. The mean SUVmax value of the tumor in the M1 group of patients was 15.96±4.29, which was higher than that of the M0 group of patients was 14.57±8.26.¹⁸FDG-PET/CT detected 100% of primary tumor lesions in the lung, ¹⁸FDG-PET/CT accurately diagnosed stage T at 71.88%, higher than CT with 68.75%, accurately diagnosed stage T at 68.75%. N segment at 81,25%, higher than CT with 75%. Sensitivity, specificity, positive predictive value, negative predictive value of ¹⁸FDG-PET/CT in the diagnosis of stage N are: 100%; 68,42%; 68,42% and 100%.

*Keywords: Non-small cell lung cancer, ¹⁸FDG-PET/CT, SUVmax.