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Date Published: 09/02/2026
Abstract Views: 5
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DOI: https://doi.org/10.55046/vjrnm.60.1491.2025
Issue
No. 60 (2025)
Section
Scientific research
How to Cite
NguyenThuHuong, Bùi, T. P. T., Trần, T. H., & Đặng, T. N. A. (2025). Management of Non-Mass Enhancement on Breast MRI: Diagnostic Challenges and Clinical Strategies. Vietnamese Journal of Radiology and Nuclear Medicine, 60, 100-108. https://doi.org/10.55046/vjrnm.60.1491.2025

Management of Non-Mass Enhancement on Breast MRI: Diagnostic Challenges and Clinical Strategies

TS.BS. Nguyễn Thu Hương1, , Ths.Bs. Bùi Thị Phương Thảo2, Thị Huệ Trần2, Thị Ngọc Anh Đặng2
1 Bệnh Viện đa khoa quốc tế Vinmec Times City
2 Bệnh viện đa khoa quốc tế Vinmec Times City

Main Article Content

Abstract

Non-mass enhancement (NME) on breast magnetic resonance
imaging (MRI) is a diagnostically challenging entity that can be easily
confused with background parenchymal enhancement and physiological
changes. This article provides an overview of the concept, imaging
features, and diagnostic challenges of NME according to BI-RADS, while
also analyzing clinical management strategies based on multimodality
correlation and histopathological results. Sources include the American
College of Radiology Breast Imaging Reporting and Data System (ACR
BI-RADS, 5th edition, 2013), recent international studies, and illustrative
clinical cases from local practice. The article highlights the role of risk
stratification (BI-RADS 3, 4a, 4b), indications for MRI-guided biopsy
versus alternative modalities such as ultrasound and mammography,
as well as the value of short-term follow-up in reducing unnecessary
biopsies. Future research prospects focus on refining grading criteria for
NME and standardizing MRI-guided biopsy protocols. In conclusion, the
management of NME requires a comprehensive approach, taking into
account clinical context and individual risk factors to optimize diagnostic
accuracy and treatment outcomes.

Article Details

References

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