The role of computed tomographic angiography in diagnosing intracranial arterial stenoocclusive disease in ischemic stroke patient
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Abstract
SUMMARY
Background: Diagnosis of intracranial arterial stenooclusive
disease and identification of intracranial atherosclerosis related occlusions (ICAS-O) in ischemic stroke patients is extremely important in order to plan a correct therapeutical approach. Few studies to date have examined the role of computed tomographic angiography (CTA) in diagnosing intracranial stenosis and predicting ICAS-related occlusions.
Objective: To determine whether there is any correlation between
CTA-determined truncal-type occlusion (TTO) and ICAS-related occlusions. To compare CTA to digital subtraction angiography (DSA) for detecting and measuring intracranial arterial stenoocclusive disease.
Methods: We reviewed 129 ischemic stroke patients who underwent CTA and DSA. The occlusion and degree of stenosis of each intracranial arteries were calculated by WASID method. Occlusion type was classified
as TTO or branching-site occlusion (BTO) on CTA. ICAS-O was detected by evaluating of underlying fixed focal stenosis (FFS) on DSA.
Results: A total of 423 intracranial arteries were analyzed. CTA detected intracranial artery occlusion with sensitivity and specificity, and NPV 97,8%, 98,6% và 98,9% respectively. For detection of 50%-99% stenosis, CTA had 89,7% sensitivity and 98,2% specificity. TTO was more frequent in ICAS-O group than in the embolic group (78,1% versus 8,5%, p < 0,001).
Conclusions: Compared to DSA, CTA has high sensitivity and specificity for diagnosing intracranial arterial stenooclusive disease. Preprocedural TTO on CTA is related to postprocedural ICAS-O in ischemic stroke patients.
Article Details
Keywords
Đột quỵ nhồi máu não cấp, hẹp tắc động mạch nội sọ (HTDMNS), tắc động mạch kiểu thân, tắc do xơ vữa động mạch nội sọ, chụp cắt lớp vi tính mạch máu (CTA), chụp mạch máu não xóa nền (DSA)
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