Value of mr diffusion tensor imaging and arterial spin labeling in grading of astrocytomas
Main Article Content
Abstract
Objectives: The purpose of this study was to determine the value of DTI and ASL in preoperative predicting the histological grade of astrocytomas.
Methods: Retrospective study with 29 patients in Choray Hospital, in 01/2017-12/2019, with histological verified astrocytomas. DTI, ASL were preoperatively performed.
Results: The mean age # 42.48 years. The ratio of men/women is 0.93/1. The FA, CBF, rCBF values of LGA were significantly lower than those of HGA (p < 0.05). With a threshold of FA of 0.224, a threshold of rCBF of 3.06 ml/100g/minute, DTI and ASL has the same sensitivity, specificity, PPV, NVP, accuracy of 76.2%, 87.5%, 94.1%, 58.3%, 79.3%. AUC of DTI is 75% and AUC of ASL is 85%.
Conclusion: FA and CBF, rCBF values can distinguish between high grade and low grade astrocytomas.
Article Details
Keywords
MR diffusion tensor imaging,, arterial spin labeling,, fractional anisotrophy (FA),, cerebral blood flow (CBF),, astrocytomas, histological grade.
References
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