Value of mr diffusion tensor imaging and arterial spin labeling in grading of astrocytomas

Dr Nguyen Thi Bao Ngoc1, Dr Le van Phuoc2
1 Imaging dept Xuyen A Hospital
2 Imaging dept Cho Ray Hospital

Main Article Content

Abstract

Objectives: The purpose of this study was to determine the value of DTI and ASL in preoperative predicting the histological grade of astrocytomas.
Methods: Retrospective study with 29 patients in Choray Hospital, in 01/2017-12/2019, with histological verified astrocytomas. DTI, ASL were preoperatively performed.
Results: The mean age # 42.48 years. The ratio of men/women is 0.93/1. The FA, CBF, rCBF values of LGA were significantly lower than those of HGA (p < 0.05). With a threshold of FA of 0.224, a threshold of rCBF of 3.06 ml/100g/minute, DTI and ASL has the same sensitivity, specificity, PPV, NVP, accuracy of 76.2%, 87.5%, 94.1%, 58.3%, 79.3%. AUC of DTI is 75% and AUC of ASL is 85%.
Conclusion: FA and CBF, rCBF values can distinguish between high grade and low grade astrocytomas.

Article Details

References

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