Article Sidebar
Views PDF: 68
Characteristics of myocardial perfusion on SPECT at the post - infarct affection
Main Article Content
Abstract
SUMMARY
Aims: the purpose of our study was to evaluate characteristics of myocardial perfusion defects in Tc99msestamibi gated SPECT myocardial perfusion imaging (MPI).
Subjects and methods: 119 post-myocardial infarction (MI) patients were underwent gated SPECT in Nuclear Medicine
Department, 108 Central Military Hosspital from March 2007 to May 2010.
Results: in gated SPECT MPI, reversible, mixed and fixed perfusion defects were detected in 63.9%, 18.5% and 17.6%,
respectively. In patient group with ESV ≥ 70 ml, SSS and SRS were significantly higher in group with ESV < 70 ml (18.63 ± 5.02
and 15.58 ± 4.99 vs 14.49 ± 4.83 and 11.15 ± 4.63 (p<0,001). There were significant correlations between SRS and SSS
with WMS (r = 0.68, p<0.001 and r = 0.61, p<0.001). In patient group with EF ≤ 40%, SSS and SRS were significantly higher
in patients with ESV>40% (19.83 ± 4.36 and 17.07 ± 4.58 vs 15.50 ± 5.2 và 12.13 ± 4.85; p<0.001). There were correlation
between SRS and SSS with EF (r = - 0.47, p < 0.001) và SSS (r = -0.44, p<0.001).
Conclusions: In post-MI patients, fixed, reversible and mixed defects are frequently detected in SPECT MPI. The extent
and severity of perfusion defects are significantly correlated with wall motion, left ventricular volume and ejection fraction
evaluated by gated SPECT MPI.
Article Details
References
1. Lê Ngọc Hà (2005), “Tổng quan về tim mạch hạt nhân”, Chuyên đề hội nghị khoa học chuyên ngành tim mạch toàn quân 2005, Tạp chí y học Việt Nam, ISSN 0686-3174, tập 316, tr 334 –345.
2. Lê Ngọc Hà (2006), “Phương pháp chụp xạ hình tưới máu cơ tim trong chẩn đoán bệnh ĐM vành”, Bài giảng bệnh tim mạch, Viện nghiên cứu khoa học y - dược học lâm sàng 108, tr 21 – 27.
3. Lê Ngọc Hà (2010), “Nghiên cứu đặc điểm tổn thương trên xạ hình Gated SPECT tưới máu cơ tim”, Tạp chí y học thực hành số 715, tr 25-29.
4. Hansen Ch.L., Goldstein R.A., Akinboboye O.O. et al (2007), “ASNC Imaging Guidelines For Nuclear Cardiology Procedures: Myocardial perfusion
and function: Single photon emission computedtomography”, J Nucl Cardiol; 14:e39-60.
5. Mahmarian J.J., Dwivedi G., Lahiri T. (2004), “Role of nuclear cardiac imaging in myocardial infarction: Postinfarction risk stratification”, J Nucl Cardiol;11: pp.186-209.
6. Mahmarian J.J., Shaw L.J., Filipchuk N.G. et al (2006), “A Multinational Study to Establish the Value of Early Adenosine Technetium-99m Sestamibi Myocardial Perfusion Imaging in Identifying a Low-Risk Group for Early Hospital Discharge After Acute Myocardial Infarction” , J Am Coll Cardiol, 48: pp.2448 –57.
7. Ndrepepa G., Mehilli J., Martinoff S. et al (2007), “Evolution of Left Ventricular Ejection Fraction and its Relationship to Infarct Size After Acute Myocardial Infarction”, J Am Coll Cardiol; 50: pp.149–56.