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Characteristics of myocardial perfusion on SPECT at the post - infarct affection
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Abstract
SUMMARY
Aims: the purpose of our study was to evaluate characteristics of myocardial perfusion defects in Tc99msestamibi gated SPECT myocardial perfusion imaging (MPI).
Subjects and methods: 119 post-myocardial infarction (MI) patients were underwent gated SPECT in Nuclear Medicine
Department, 108 Central Military Hosspital from March 2007 to May 2010.
Results: in gated SPECT MPI, reversible, mixed and fixed perfusion defects were detected in 63.9%, 18.5% and 17.6%,
respectively. In patient group with ESV ≥ 70 ml, SSS and SRS were significantly higher in group with ESV < 70 ml (18.63 ± 5.02
and 15.58 ± 4.99 vs 14.49 ± 4.83 and 11.15 ± 4.63 (p<0,001). There were significant correlations between SRS and SSS
with WMS (r = 0.68, p<0.001 and r = 0.61, p<0.001). In patient group with EF ≤ 40%, SSS and SRS were significantly higher
in patients with ESV>40% (19.83 ± 4.36 and 17.07 ± 4.58 vs 15.50 ± 5.2 và 12.13 ± 4.85; p<0.001). There were correlation
between SRS and SSS with EF (r = - 0.47, p < 0.001) và SSS (r = -0.44, p<0.001).
Conclusions: In post-MI patients, fixed, reversible and mixed defects are frequently detected in SPECT MPI. The extent
and severity of perfusion defects are significantly correlated with wall motion, left ventricular volume and ejection fraction
evaluated by gated SPECT MPI.
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