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Date Published: 11/07/2022
Online Published: 11/07/2022
Abstract Views: 127
Views PDF: 136
DOI: https://doi.org/10.55046/vjrnm.18.367.2014
Issue
No. 18 (2014)
Section
Scientific research
How to Cite
Nguyen, H. T. N., & Le, V. P. (2022). Evaluattion of the correlation between serum ferritin and iron overload of liver, spleen and heart in β -Thalassaemia major patients by mri t2* method. Vietnamese Journal of Radiology and Nuclear Medicine, 18, 11-16. https://doi.org/10.55046/vjrnm.18.367.2014

Evaluattion of the correlation between serum ferritin and iron overload of liver, spleen and heart in β -Thalassaemia major patients by mri t2* method

Ho Thi Nga1, Le Van Phuoc1,
1 Department of Diagnostic Imaging, Cho Ray Hospital

Main Article Content

Abstract

SUMMARY


Objective: MRI T2* is an accurate non-invasive method for assessing organ iron overload. This study evaluated the correlation between serum ferritin and iron overload of liver, spleen and heart in β - thalassaemia major patients by MRI T2* method.
Materials-Methods: A cross-section, descriptive study was designed. We used MRI-T2* to evaluated the correlation between
serum ferritin and iron overload of liver, spleen and heart in 24 thalassaemia major patients admitted in ChoRay hospital from
10/2013 to 1/2014.
Results: Moderate negative correlation between serum ferritin and liver, spleen MRI T2* relaxation time (r = 0,57 and 0,755) and a weak negative correlation between serum ferritin and heart MRI T2* relaxation time (r = 0,303). Liver and heart MRI T2* readings were poorly correlated (r = 0, 28).
Conclusion: MRI T2* is useful to evaluate the iron overload status in β thalassemia patients.

Article Details

Keywords

Serum ferritin, MRI T2*, β -Thalassemia major

References

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