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Date Published: 11/07/2022
Online Published: 11/07/2022
Abstract Views: 152
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DOI: https://doi.org/10.55046/vjrnm.28.474.2017
Issue
No. 28 (2017)
Section
Scientific research
How to Cite
Mai, H. S., & Le, N. H. (2022). 18Flourodeoxyglucose positron emission tomography/ computer tomography (18f-fdg pet/ct) for extranodal non hodgkin lym. Vietnamese Journal of Radiology and Nuclear Medicine, 28, 11-16. https://doi.org/10.55046/vjrnm.28.474.2017

18Flourodeoxyglucose positron emission tomography/ computer tomography (18f-fdg pet/ct) for extranodal non hodgkin lym

Mai Hong Son1, Le Ngoc Ha1,
1 Department of Nuclear Medicine, Central Military Hospital 108

Main Article Content

Abstract

SUMMARY


Background: the aim of our study to investigate the role of 18F-FDG PET/CT for extranodal lymphoma non Hodgkin in staging
and treatment response’s assessment. Methods: In our center, a total of 38 consecutive B-cell non- Hodgkin extranodal lymphoma patients were newly diagnosed between December 2013 to January 2016. All these patients were undergone 18F-FDG PET/CT scan before treatment, after 3- cycle and 6-cycle chemotherapy.
The assessment criteria were followed by modified Ann Aborr for staging and Lugano 2015 for treatment response.
Results: there were 13,2% of patients in stage IE, 7,9% in stage II3, 21,1% in stage IIIE and 47,9% ín stage IV. According to PET/CT staging, 56,2% of patients were upstaging in comparision to CT and 26,3% of patients have been changed in treatment’s stratergies. Kappa statistics revealed that CT and PET/CT showed fair agreement for the detection of extranodal lymphoma. After 6-cycle chemotherapy, 26/38 patients had no evidence of residuals or relapse and 7/38 patients showed partial response and 5/38 patients was in advanced diseases on PET/CT imaging. The positive and negative PET/CT after 3 cylces chemotherapy
may predicted the treatment’s response after 6 cylces (p=0.4).
Conclusions: 18F-FDG PET/CT has higher value than CT for staging and important role in assessment of treatment’s response
of extranodal lymphoma non Hodgkin patients.

Article Details

Keywords

non - Hodgkin lymphoma, Positron Emission Tomography/Computed Tomography, treatment response assessment

References

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