Research into the value of b-mode ultrasound and strain elastography ultrasound in the diagnosis of breast cancer

Dr Nguyen Thi Thu Thao1, Dr Luu Hong Nhung1, Dr Vu Dang Luu1, professor Pham Minh Thong1
1 Department of Diagnostic Imaging Bach Mai hospital photo

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Abstract

A diagnostic test study was conducted at Bạch Mai hospital to evaluate the efficacy of Ultrasound Strain Elastography in diagnosis of breast masses.
Result: 22 patients with 24 lesions were prospectively evaluated by B-mode ultrasound and strain elastography, followed by the core biopsy. The sensitivity, specificity, positive predictive value, negative predictive value, accuracyfor the B-mode Ultrasound were 94.1%, 57.1%, 84.2%, 80%, 83,3%. Elastography combined with B-mode ultrasound improved the value in diagnosis, the sensitivity, specificity, positive predictive value, negative predictive value, accuracywere 100%, 71,4%, 89,4%, 100%, 91,7%.
Conclusion: Strain elastography can better diagnose BI-RADS 3 and 4a lesions, especially when combined with B-mode breast
ultrasound, which may increase or decrease the BI-RADS level, improvethe accuracy from 83,3% to 91,4%.

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References

1. Ferlay J, Soerjomataram I, and Dikshit R et al, Cancer incidence and mortality worldwide: Sources, methods, and major patterns in Globocan 2012. Int Cancer, 2012. 10: p. 1002.
2. Bùi Diệu,Một số bệnh ung thư ở phụ nữ. 2011, Nhà xuất bản Y học, Hà Nội.
3. Carl J. D’Orsi et al, ACR BI-RADS® Atlas Breast Imaging Reporting and Data System. 2013.
4. Ophir J and Elastography: A quantitative method for imaging the elasticity of biological tissues. Ultrason Imaging, 1991. 13: p. 111-134.
5. William H. Hindle, Leonard Davis et al, Clinical value of mammography for symptomatic 1women 35 years of age and younger. Am J Obstet Gynecol, 1997. 6(1): p. 1484-1490.
6. Foxcroft LM, Evans EB, and Porter AJ et al, The diagnosis of breast cancer in women younger than 40. Breast, 2004. 13(4): p. 297-306.
7. F.K.W. Schaefer, I. Heer et al, Breast ultrasound elastography—Results of 193 breast lesions in a prospectivestudy with histopathologic correlation. European Journal of Radiology, 2011. 77: p. 450-456.
8. Ito A et al, Breast Disease: Clinical Application of US Elastography for Diagnosis. Radiology, 2006. 239(2): p. 341-350.
9. Kristina Bojanic et al, Implementation of Elastography Score and Strain Ratio in Combination with B-Mode Ultrasound Avoids Unnecessary Biopsies of Breast Lesions. Ultrasound in Medicine & Biology, 2017. 43(4): p. 804-816.
10. Thomas A, Degenhardt F, Farrokh A et al, Significant differentiation of focal breast lesions: Calculation of strain ratio in breast sonoelastography. Acad Radiol 2010. 17: p. 558-563.
11. Gheonea IA, Stoica Z, Bondari S et al, Differential diagnosis of breast lesions using ultrasound elastography. Indian J Radiol Imaging, 2011. 21: p. 301-305.
12. Liu XJ, Zhu Y, Liu PF et al, Elastography for breast cancer diagnosis: a useful tool for small and BI-RADS 4 lesions. Asian Pac J Cancer Prev 15: p. 10739-10743.
13. Barr RG, Zhang Z et al, Probably benign lesions at screening breast US in a population with elevated risk: prevalence and rate of malignancy in the ACRIN 6666 trial. Radiology, 2013. 269: p. 701-712.
14. RICHARD G. BARR, WFUMB guidelines and recommendations for clinical use of ultrasound elastography: Part 2: breast. Ultrasound Med Biol 2015. 41: p. 1148-1160.
15. Menezes R, Sardessai S et al, Correlation of strain elastography with conventional sonography and FNAC/biopsy. J Clin Diagn Res 2016. 10: p. 5-10.