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Date Published: 11/07/2022
Online Published: 11/07/2022
Abstract Views: 87
Views PDF: 131
DOI: https://doi.org/10.55046/vjrnm.28.477.2017
Issue
No. 28 (2017)
Section
Scientific research
How to Cite
Le, V. P., Bui, A. T., & Bui, N. T. (2022). The value of magnetic resonance spectroscopy in diagnosis of prostate cancer. Vietnamese Journal of Radiology and Nuclear Medicine, 28, 24-28. https://doi.org/10.55046/vjrnm.28.477.2017

The value of magnetic resonance spectroscopy in diagnosis of prostate cancer

Le Van Phuoc1, Bui Anh Thang2, Bui Ngoc Thuan3,
1 Cho Ray hospital
2 Medical University Pham Ngoc Thach
3 Can Tho Central General Hospital

Main Article Content

Abstract

SUMMARY


Purpose: The aim of study was to determine the value of MRS in diagnosis of prostate carcinoma especially for differentiating
begnin from malignant lesion of the prostate.
Materials and methods: During a period of 4/2014 to 6/2016, 25 consecutive patients with elevated PSA level or clinical suspiciousness were evaluated with MRS of the prostate. The
results were confirmed by TRUS-guided biopsy. We compare two groups (prostate carcinoma/PCa and prostate non-caricnoma/
PNCa) by variant: mean of the choline plus creatine -to- citrate. Analyzing ROC curve to find the value of MRS in differentiating begnin from malignant tissue of the prostate.
Results: Patients range in age from 40 to 89 years (mean 71±12year). 08 patients were confirmed to have PNCa (32%), whereas 17 patients had PCa (68%). The mean of (Cho+ Cr)/
Ci values for PNCa and PCa were 0.50± 0.31 and 2.64± 1.22 respectively. The mean of (Cho+Cr)/ Ci value of PCa was significantly higher than PNCa (p<0.05). On ROC curve, using discrimination threshold of (Cho+Cr)/ Ci is 0.84, the MRS provided a sensitivity of 94.1%, specificity of 87.5% for differentiating NPCa
from PCa.
Conclusion: Magnetic Resonance Spectroscopy of the prostate can be use to differentiate begnin from malignant tissue with high accuracy.

Article Details

Keywords

Prostatic carcinoma, non-carcinoma, Magnetic resonance spectroscopy, TRUS

References

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