NGHIÊN CỨU HỘI CHỨNG CHUYỂN HÓA TRÊN BỆNH NHÂN GAN NHIỄM MỠ ĐẾN KHÁM TẠI PHÒNG BẢO VỆ SỨC KHOẺ CÁN BỘ TỈNH THỪA THIÊN HUẾ

Dr Huynh Cong Minh1, Dr Van Thi Thanh Van1, Dr Le Viet Kham1, Dr Huynh The Thien Giac1, Dr Huynh Thi Sau1, Dr Nguyen Thi Thanh Thuy1
1 Rolling Health Protection Department Department of Thua Thien Hue province

Main Article Content

Abstract

Objectives: To study the metabolic syndrome in fatty liver patients examed yearly at Thua Thien Hue Officer’s Health Care and
Protect Department to find out the association between metabolic syndrome and fatty liver on the study subjects.
Subjects and methods: 342 patients with 265 men (77.49%) and 77 females (22.51%) with ultrasound fatty liver examed at Thua Thien Hue Officer’s Health Care and Protect Department, from 02- 09/2016. Diagnosis of metabolic syndrome according to IDF criteria (2009).
Results: The metabolic syndrome prevalence was high at 34.21% in both sexes (37.74% in male, 22.08% in female), this rate
was increased with age and BMI, especially age at 50-69 is 46% in male and 40% in female; and at 70 years old and more is 100%. The metabolic syndrome rate was also elevated in subjects with grade II (about 60%) and grade III (over 80%) of fatty liver. There was a statistically significant (p <0.05) correlation between the grade of fatty liver and the abdominal component on the study subjects. In addition, the risk of metabolic syndrome presented in patients with fatty liver at grade II or higher was significantly higher.
Conclusions: The metabolic syndrome prevalence was high in patients with grade II or III of fatty liver, particularly high in older
patients with fatty liver disease, and increasely in BMI. There was a risk of metabolic syndrome in patients with grade II or higher fatty liver.

Article Details

References

1. Bộ môn Nội-Đại học Y Dược Huế (2008), “Hội chứng chuyển hóa”, Giáo trình sau đại học chuyên ngành Nội tiết và chuyển hóa, NXB Đại Học Huế, tr.313-357
2. Lê Văn Chi (2008), “Sinh lý bệnh Hội chứng chuyển hóa”, Tạp chí Y Học Thực Hành, (616 + 617), tr. 134-147.
3. Nguyễn Thị Việt Hồng, Dương Hồng Thái (2013), “Nghiên cứu mối liên quan giữa HCCH với các đặc điểm lâm sàng ở bệnh nhân gan nhiễm mỡ không do rượu”, Tạp chí Y Học Thực Hành, 866(4), tr. 82-86.
4. Nguyễn Thị Thùy Linh, Trần Bảo Nghi (2012), “Nghiên cứu hội chứng chuyển hóa ở người cao tuổi có gan nhiễm mỡ không do rượu”, Tạp chí Y Học TP. Hồ Chí Minh, 16(1), tr. 97-100.
5. Nguyễn Phước Bảo Quân (2008), “Gan”, Siêu âm bụng tổng quát, tr. 115-234.6. Alberti K. G., Eckel R. H., Grundy S. M. et al. (2009), Harmonizing the Metabolic Syndrome, Circulation, 120; pp.1640-1645.
7. Corina Radu, Mircea Grigorescu et al. (2008), Prevalence and Associated Risk Factors of Non- Alcoholic Fatty Liver Disease in Hospitalized Patients, J Gastrointestin Liver Disease, 17 (3), pp.255-260.
8. Masahide Hamaguchi, Noriyuki Takeda et al. (2012), Identification of individuals with non-alcoholic fatty liver disease by the diagnostic criteria for the metabolic syndrome, World J Gastroenterol, 18(13), pp.1508-1516.
9. Mauro Karnikowski, Cláudio Córdova et al. (2007), Non-alcoholic fatty liver disease and metabolic syndrome in Brazilian middle-aged and older adults, Sao Paulo Med J., 125(6), pp.333-337.
10. Scott Rector R, Thyfault John P et al. (2008), Non-alcoholic fatty liver disease and the metabolic syndrome: An update, World J Gastroenterol, 14(2), pp. 185-192.