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Date Published: 11/07/2022
Online Published: 11/07/2022
Abstract Views: 94
Views PDF: 60
DOI: https://doi.org/10.55046/vjrnm.29.512.2018
Issue
No. 29 (2018)
Section
Scientific research
How to Cite
Nguyen, H. L., Vo, V. D., & Ha, T. N. (2022). Placental mesenchymal dysplasia: case report. Vietnamese Journal of Radiology and Nuclear Medicine, 29, 105-111. https://doi.org/10.55046/vjrnm.29.512.2018

Placental mesenchymal dysplasia: case report

Dr Nguyen Hoang Long1, Dr Vo Van Duc1, Dr Ha To Nguyen2
1 Department of Obstetrics and Gynecology – Hue University of Medicine and Pharmacy
2 Department of Diagnostic Imaging – Tu Du Hospital

Main Article Content

Abstract

Introduction: Placental mesenchymal dysplasia (PMD) is a rare vascular anomaly characterized by mesenchymal stem villous hyperplasia. it is important to distinguish PMD from partial hydatidiform mole or a twin pregnancy with a normal fetus and coexistent complete mole and placenta mosacism due to the completely difference in prediction and prognosis. It is also crucial to manage PMD because the association between this problem and severe pregnancy outcomes.
Case report: 02 outpatient PMD cases was diagnosed and monitored at Obstetrics and Gynecology Department, Hue University Hospital during pregnancy. The placental histopathologic and grossly findings correspond to the diagnosis of PMD and the prenatal ultrasound findings. The results was similar with other publications worldwide. There was no severe pregnancy outcomes on two pregnant woman, but 1 of 2 fetus was suspected intrauterine growth restriction.
Conclusion: It is necessary to evaluate morphology carefully to make a sutable diagnosis. Amniocentesis should be thought. PMD relates to some pregnancy outcomes, however it is a benign disease so we should evaluate carefully the fetal growth and pregnancy outcomes

Article Details

Keywords

Placental mesenchymal dysplasia, fetal growth, pregnancy outcomes

References

1. Pham T, Steele J, Stayboldt C, Chan L, Benirschke K. Placental mesenchymal dysplasia is associated with high rates of intrauterine growth
restriction and fetal demise: a report of 11 new cases and a review of the literature. Am J Clin Pathol 2006;126:67–78.
2. Akiko Tanuma et al, Prenatal imaging and pathology of placental mesenchymal dysplasia: a report of three cases, Case Rep. Perinat. Med. 2016; 5(1): 9–14.
3. V. Ulker et al, Placental mesenchymal dysplasia: A rare clinicopathologic entity confused with molar pregnancy, Journal of Obstetrics and
Gynaecology, April 2013; 33: 246–249.
4. Maria Chiara Sudano et al, Placental mesenchymal dysplasia, a case of intrauterine sudden death in a normal-sized fetus, Journal of Prenatal
Medicine 2013; 7 (1): 9-11.
5. Gregory W. Woo et al, Placental mesenchymal dysplasia, Am J Obstet Gynecol 2011.
6. Vaisbuch E, Romero R, Kusanovic JP, Erez O, Mazaki-Tovi S, Gotsch F. Three dimensional sonoraphy of placental mesenchymal dysplasia and its differential diagnosis. J Ultrasound Med. 2009;28:359–68.
7. A. Nayeri, B. West, Grossetta Nardini, A. Copel, K. Sfakianaki, Systematic review of sonographic findings of placental mesenchymal dysplasia and
subsequent pregnancy outcome, Ultrasound Obstet Gynecol 2013; 41: 366–374.
8. F J Paradinas, N J Sebire, R A Fisher, Pseudopartial moles: placental stem vessel hydrops and the association with Beckwith-Wiedemann syndrome and complete moles, Histopathology 2001,39, 447±454.