Imaging characteristics and diagnostic value of SPECT myocardial perfustion scintigraphy with combined supine - prone acquisition in diagnosis of coronary artery diseases

Le Quoc Khanh1, Le Ngoc Ha1,
1 Department of Nuclear Medicine, Central Military Hospital 108

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Abstract

SUMMARY


Abstract: The aim of the study is to determine the imaging characteristics and diagnostic values of the combined supine - prone
myocardial perfusion SPECT in comparison with supine alone acquisition.
Methods: 59 CAD suspected patients were underwent Tc-99m sestamibi ECG - gated myocardial perfusion SPECT with combined
supine - proneacquisition protocol to reduce attenuation defects in supine images. The results of MPI were compared with the coronary angiogram.
Results: The sensitivity and specificity of the combined acquisitionprotocol were 76%, 94.1% respectively. There is no significant
difference in the sensitivity between the two patient’s position acquisition. However, specificity was significantly improved in the combined acquisition (94.1% vs. 70.6%), especially in male (96.4% vs. 71.4%) and
overweight patient’s groups (BMI> 23) (94.4% vs 61.1%).
Conclusions: The combined supine - prone acquisitionprotocol did significantly improved the specificity ofmyocardial perfusion SPECT,
especially in the overweight and males.

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References

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