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Date Published: 08/07/2022
Online Published: 08/07/2022
Abstract Views: 90
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DOI: https://doi.org/10.55046/vjrnm.30.523.2018
Issue
No. 30 (2018)
Section
Scientific research
How to Cite
Nguyen, D. H., Pham, C. H., & Than, V. S. (2022). Noninvasive evaluation of glioma grade using perfusion and multivoxel 3d proton mr spectroscopy. Vietnamese Journal of Radiology and Nuclear Medicine, 30, 87-92. https://doi.org/10.55046/vjrnm.30.523.2018

Noninvasive evaluation of glioma grade using perfusion and multivoxel 3d proton mr spectroscopy

Nguyen Duy Hung1,2, Pham Chu Hoang3, Than Van Sy1,2,
1 Department of Diagnostic Imaging, Hanoi Medical University
2 Department of Diagnostic Imaging at Viet Duc Hospital
3 Department of Diagnostic Imaging, Hanoi Medical University Hospital

Main Article Content

Abstract

SUMMARY
The purpose of this study was to clarify the usefulness of perfusion and multivoxel 3D proton MR spectroscopy in glioma grading. Study included 85 patients underwent preoperative conventional MR Imaging, multivoxel proton MR spectroscopy and histopathologically determined gliomas after stereotactic biopsy or partial resection. Receiver operative characteristic (ROC)
curve analyses were performed to asscess the cutoff of rCBV and metaboite parameters of which the sensitivity and specificity are highest.A cut-off value of 2,56 for rCBV resulted in sensitivity, specificity of 86,54%, 75,76%, respectively. The cut-off value was taken as 2,76 in the Cho/NAA ratio provided sensitivity, specificity of 89,66%; 88%, respectively. The combination of rCBV and Cho/NAA ratio provided sensitivity, specificity of 71,15%; 78,79%, respectively. rCBV and Cho/NAA can increase the
ability of glioma grading preoperatively.

Article Details

Keywords

glioma, perfusion MR, spectroscopy MR

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