Value of multidetector ct in preoperative assessment of the vascular invasion in pancreatic adenocarcinoma

Dr Nguyen Tri Dung1, Dr Le Van Phuoc1, Dr Pham Ngoc Hoa1
1 Diagnostic Imaging Department - Cho Ray Hospital

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Abstract

Object: The purpose of this study is to assess the accuracy of multidetector computed tomography (MDCT) in preoperative determination of the vascular invasion in pancreatic adenocarcinoma.
Materials and methods: Multidetector computed tomography, surgery, and pathological results of 39 patients with pancreatic
adenocarcinoma were evaluated retrospectively. MDCT findings were compared with surgical findings to determine the sensitivity, specificity, positive predictive value (PPV), negative predictive value (NPV), and accuracy of MDCT in determining the vascular invasion.
Results: 39 patients (21 males, mean age: 58,8 years) underwent surgery. The sensitivity, specificity, PPV, NPV, and accuracy of MDCT in determining the vascular invasion of pancreatic adenocarcinomas were 88,9%, 96,9%, 86,5%, 97,5% and 95,9% respectively.
Conclusion: The accuracy of MDCT is high in preoperative determination of the vascular invasion in pancreatic adenocarcinoma.

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References

1. Brennan et al (2007), “Comprehensive Preoperative Assessment of Pancreatic Adenocarcinoma with 64-Section Volumetric CT”, Radiographics. 27(6), pp. 1653-1666.
2. C. Caraiani et al (2011), “Computer-tomographic signs of vascular invasion in tumors of the pancreas”, European Society of Radiology, p1-14.
3. İşcanlı et al (2014), “Assessment of surgical resectability of pancreatic adenocarcinomas with multidetector computed tomography: What are the possibilities and problems?”, Turk J Gastroenterol 25, p.416-423.
4. Kaneko (2010), “Performance of multidetector computed tomographic angiography in determining surgical re sectability of pancreatic head adenocarcinoma”, J Comput Assist Tomogr. 34, p.732-738.
5. Li et al (2005), “Pancreatic adenocarcinoma: the different CT criteria for peripancreatic major arterial and venous invasion.”, J Comput Assist Tomogr. 29(2), p.170-175.
6. Li et al (2006), “Pancreatic adenocarcinoma: signs of vascular invasion determined by multi-detector row CT”, The British Journal of Radiology, p.880-887.
7. Lu et al (1997), “Local staging of pancreatic cancer: criteria for unresectability of major vessels as revealed by pancreatic-phase, thin-section helical CT.”, AJR, pp.1439-1443.
8. M.M. Al-Hawary et al (2013), “Staging of Pancreatic Cancer: Role of Imaging”, Seminars in roentgenplogy, pp. 245-252.
9. Nakayama Y et al (2001), “Vascular encasement by pancreatic cancer: correlation of CT findings with surgical and pathologic results”, J Comput Assist Tomogr. 25(3), p.337-342.
10. O’Malley ME et al. (1999), “Adenocarcinoma of the head of the pancreas: determination of surgical unresectability with thin-section pancreatic-phase helical CT”, AJR. 173(6), p.1513-1518.
11. Omar Hassanen et al (2014), “Assessment of vascular invasion in pancreatic carcinoma by MDCT”, The Egyptian Journal of Radiology and Nuclear Medicine. 45, p.271-277.
12. P. Michl et al (2006 ), “Evidence-based diagnosis and staging of pancreatic cancer”, Best Practice & Research Clinical Gastroenterology. 20(2), pp. 227–251.
13. Sahani (2011), Abdominal Imaging, Saunders, p.721-734
14. Van Delden OM et al (1998), “Laparoscopic ultrasonography for abdominal tumor staging”, Eur Radiol 8, p.1405-1408.
15. Zaky et al (2017), “Tumor-Vessel Relationships in Pancreatic Ductal Adenocarcinoma at Multidetector CT: Different Classification Systems and Their Influence on Treatment Planning”, Radiographics, pp.93-112.