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Date Published: 08/07/2022
Online Published: 08/07/2022
Abstract Views: 115
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DOI: https://doi.org/10.55046/vjrnm.31.556.2018
Issue
No. 31 (2018)
Section
Scientific research
How to Cite
Mai, H. S., Le, N. H., Vu, D. C., & Nguyen, T. L. (2022). Preliminary evaluation of F-18 FDG PET findings in pediatric patients with autism. Vietnamese Journal of Radiology and Nuclear Medicine, 31, 93-100. https://doi.org/10.55046/vjrnm.31.556.2018

Preliminary evaluation of F-18 FDG PET findings in pediatric patients with autism

Dr Mai Hong Son1, Dr Le Ngoc Ha1, Dr Vu Duy Chinh2, Dr Nguyen Thanh Liem2
1 Department of Nuclear Medicine Hospital TUQ108
2 International General Hospital Vinmec

Main Article Content

Abstract

Objectives: the purpose of this study was to evaluate F-18 FDG Positron Emission Tomography (PET) findings in pediatric patients with autism.
Subjects and methods: This study includes 15 autism pediatric patients who were diagnosed at the Vinmec international hospital from January 2017 to May 2017 and five oncology patients without neurology’s diseases underwent to whole body PET scan (from vertex to midthigh) were selected as control group. All patients underwent PET/CT brain examination in Nuclear Medicine Department, 108 Central Military Hospital.
Results: Mean patient age (7.1 ± 0.24). On the PET scans of the 15 patients with autism, 13 (86%) had significantly decreased
metabolic activity of both hemispheres. All of the patients had decreased metabolism in temporal, parietal and cingulate gyrus. Mean of Z-scores of autism group showed significantly decreased activity in comparison with Z-score of the control group. There were relations between clinical and grade of hypometabolism of autism.
Conclusions: hypometabolism in the brain of autism pediatric patients may present a role in diagnosis and prognosis.

Article Details

Keywords

autism pediatric patients, hypometabolism in the brain

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