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The value of dynamic subtraction MRI 3.0 Tesla technique in the angiogenesis assessment of hepatocellular carcinoma after transcatheter arterial chemoembolization
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Abstract
Objective: The value of dynamic subtraction MRI 3.0 Tesla technique in the angiogenesis assessment of hepatocellular carcinoma after transcatheter arterial chemoembolization.
Methods: A cross-sectional, retrospective descriptive study was performed on 40 patients, who had been diagnosed with HCC and treated with TACE, then do dynamic subtraction MRI 3T from 6/2021 to 6/2022 at Bach Mai hospital, Hanoi, Vietnam.
Result: The study consisted of 43 patients with 55 hepatocellular carcinoma lesions who underwent transarterial chemoembolization procedure and followed up by dynamic MRI of the liver with post processing to obtain subtraction images and compared with DSA. The subtraction images have sensitivity of 100%, specificity of 100%, PPV of 100%, and NPV of 100%. On the other hand, the dynamic images is 90,9%; 69,2%; 90,9%;69,2%; the Diffusion images is 97,7%; 61,5%; 89,6%; 88,9%. Comparative study between D-MRI and DS-MRI assessments revealed; highly significant increase in disease detection rate, sensitivity, and NPV in favor of DS-MRI in HCC patients; with highly significant difference (p < 0.01 respectively).
Conclusions: Dynamic MRI is valuable in the angiogenesis assessment of hepatocellular carcinoma after TACE, however, this value is augmented by the addition of subtraction technique especially in lesions having high signal before administration of contrast medium with sensitivity of 100%, specificity of 100%, PPV of 100%, and NPV of 100%. So we recommend adding the subtraction technique in the protocol of MRI in the follow up after transarterial chemoembolization as it increases the diagnostic confidence.
Article Details
Keywords
dynamic subtraction MRI, hepatocellular carcinoma, TACE.
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