VALUE OF DIFFUSION-WEIGHTED IMAGING IN DIFFERENTIATING TYPICAL FROM ATYPICAL MENINGIOMAS

Le Thi Bich Van1, Nguyen Hoang Lam1, Ho Xuan Tuan2, Le Van Phuoc1
1 Cho Ray Hospital
2 Danang University of Medicine and Pharmacy Technology

Main Article Content

Abstract

Objective: To determine the value of Diffusion-weighted imaging in distinguishing typical and atypical meningiomas.


Subjects and methods: The study was performed at Choray Hospital from January 2021 to August 2022, with 66 typical and atypical meningiomas patients. The descriptive retrospective cross-sectional study was performed. Compare the tumor's signal intensity and mean ADC value with the histopathological results to distinguish typical and atypical meningiomas.


Results: In 66 patients, there were 13(19.7%) male patients and 53(80.3%) female patients. The mean age of patients was 60.53 years old. The number of typical and atypical meningiomas cases was 43 (65.2%) and 23 (34.8%). There was no significant signal intensity difference between typical and atypical meningiomas (p=0.56). The mean ADC value for typical meningiomas is 0.843x10-3mm2/s and atypical is 0.737x10-3mm2/s, the difference is statistically significant with p=0.003. On the ROC curve, with an ADC cutoff of 0.780x10-3mm2/s, DWI can distinguish typical and atypical meningioma with sensitivity, specificity, PPV, NPV, and accuracy is 83.8%, 51.7%, 67.4%, 71.4%, 66.6% respectively.


Conclusion: The mean ADC value of typical meningiomas is higher than that of atypical meningiomas. DWI is valuable in the differential diagnosis of typical and atypical meningiomas.

Article Details

References

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