VALUE OF DIFFUSION-WEIGHTED IMAGING IN DIFFERENTIATING TYPICAL FROM ATYPICAL MENINGIOMAS
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Abstract
Objective: To determine the value of Diffusion-weighted imaging in distinguishing typical and atypical meningiomas.
Subjects and methods: The study was performed at Choray Hospital from January 2021 to August 2022, with 66 typical and atypical meningiomas patients. The descriptive retrospective cross-sectional study was performed. Compare the tumor's signal intensity and mean ADC value with the histopathological results to distinguish typical and atypical meningiomas.
Results: In 66 patients, there were 13(19.7%) male patients and 53(80.3%) female patients. The mean age of patients was 60.53 years old. The number of typical and atypical meningiomas cases was 43 (65.2%) and 23 (34.8%). There was no significant signal intensity difference between typical and atypical meningiomas (p=0.56). The mean ADC value for typical meningiomas is 0.843x10-3mm2/s and atypical is 0.737x10-3mm2/s, the difference is statistically significant with p=0.003. On the ROC curve, with an ADC cutoff of 0.780x10-3mm2/s, DWI can distinguish typical and atypical meningioma with sensitivity, specificity, PPV, NPV, and accuracy is 83.8%, 51.7%, 67.4%, 71.4%, 66.6% respectively.
Conclusion: The mean ADC value of typical meningiomas is higher than that of atypical meningiomas. DWI is valuable in the differential diagnosis of typical and atypical meningiomas.
Article Details
Keywords
meningiomas, typical, atypical, diffusion-weighted imaging, ADC
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