Article Sidebar
Views PDF: 558
Evaluation of erlier outcome of treatment embolization for ruptured brain arterionous malformation in children with onyx
Main Article Content
Abstract
Objective: The manifestation of clinical symptom, CT scanner, DSA imaging and evaluated earlier results of treatment embolization for rupturedbrain arteriovenous malformations (bAVM) in children with Onyx.
Methods: A prospective study was performed at National Children Hospital with treatment of ruptured bAVM by Onyx during the period from March 2017 to July 2019, including 45 patients.
Results: Twenty-Five boys and Twenty Girls with a mean age of 8.7 years,. Result in on CT: cerebral hemorrhage on Supratentorial was 77.8%, infratentorial 11.1%, intraventricular hemorrhage 57.8%. DSA: according to Spetzler – Martin grading system: grade 1: 2.2%, grade 2 60%, grade 3 33.4%, grade 4 4.4%, 57 interventional sessions of embolization were
performed, 1 to 3 sessions/patient with an average of 1.2 sessions/ patient, Complete obliteration of the AVM with Onyx was achieved in 26 of 45 patients (57,7%). Partial obliteration (>60%) was 17of 45 patients (37.7%), there were 8 patients with complications including hemorrhages and infarctions during embolization and good recovered, no died patient.
Conclusion: Endovascular treatment of ruptured bAVMs with Onyx in children seems safe and effective with low complication rates.
Article Details
Keywords
Arteriovenous malformation, Embolization, children
References
2. Thomas Blauwblomme, MD; Marie Bourgeois, MD, Long-Term Outcome of 106 Consecutive Pediatric Ruptured Brain Arteriovenous Malformations After Combined Treatment, Stroke. 2014;45:1664-1671.)
3.Mohammad El-Ghanem, a Tareq Kass-Hout, Arteriovenous Malformations in the Pediatric Population: Review of the Existing Literature, Interv Neurol. 2016 Sep; 5(3-4): 218–225.
4. Spetzler RF, Martin NA. A proposed grading system for arteriovenous malformations. J Neurosurg 1986;65:476-83.
5. Reitz M1, von Spreckelsen N, Angioarchitectural Risk Factors for Hemorrhage and Clinical Long-Term Outcome
in Pediatric Patients with Cerebral Arteriovenous MalformationsWorld Neurosurg. 89(5), P: 540-51
6. Nguyễn Thị Mỹ Linh(2015), Nghiên cứu lâm sàng và kết quả điều trị dị dạng động tĩnh mạch não đã vỡ bằng nút
mạch với Onyx tại Bệnh viện Tỉnh Nghệ an, Luận văn thạc sỹ, chuyên ngành Thần Kinh học, Đại học Y Hà nội
7. Phan Văn Đức (2015), Nghiên cứu đặc điểm lâm sàng, siêu âm doppler xuyên sọ và hình ảnh chụp mạch máu của dị dạng thông động-tĩnh mạch não, Luận văn Tiến sĩ y học, Chuyên nghành Thần kinh, Viện nghiên cứu y dược học lâm sàng 108.
8. Phạm Minh Thông, Dư Đức Chiến, Lê Đức Hinh. (2002), “Nghiên cứu đặc điểm hình ảnh dị dạng thông động tĩnh mạch não và kết quả bước đầu điều trị bằng phương pháp gây tắc qua lòng mạch”, Công trình nghiên cứu khoa học- Bệnh viện Bạch Mai, Tập 1, p. 11-9.
9. 9.van Rooij WJ1, Jacobs S, Sluzewski M, Beute GN, van der Pol B., Endovascular treatment of ruptured brain AVMs in the acute phase of hemorrhage. AJNR Am J Neuroradiol. 2012 Jun;33(6):1162-6
10. Katsaridis V, Papagiannaki C, et al (2008), “Curative embolization of cerebral arteriovenous malformations with Onyx in 101 patients”, Neuroradiology, 50(7), p. 589-97.
11. Picard L, et al (2001), “Acute spontaneous hemorrhage after embolization of brain arteriovenous malformation with N- butyl cyanoacrylate.”, J Neurology, 28, p. 147-65.